Category Archives: Prevention, Engagement and Care Cascade

Attrition of HIV-positive children from HIV services in low- and middle-income countries: A systematic review and meta-analysis

2019

INTRODUCTION: Identification and retention of HIV-positive children in HIV services is essential to ensure optimal health outcomes. This systematic review and meta-analysis examines the magnitude of attrition (loss to follow-up...

Positive affect and medication adherence in chronic conditions: A systematic review

2019

OBJECTIVE: This review aims to inform research and clinical care on the current state of knowledge on the relationship between positive affect and medication adherence. METHOD: Searches were carried out...

Definition of immunological non-response to antiretroviral therapy: A systematic review

2019

BACKGROUND: Terms and criteria to classify people living with HIV on antiretroviral therapy (ART) who fail to achieve satisfactory CD4 T cell counts are heterogeneous, and need revision and summarization....

Sexually transmitted hepatitis C virus infections: Current trends, and recent advances in understanding the spread in men who have sex with men

2019

INTRODUCTION: Hepatitis C virus (HCV) is a major public health threat. Although the recent availability of highly effective directly acting antivirals created optimism towards HCV elimination, there is ongoing transmission...

Gender-based violence and engagement in biomedical HIV prevention, care and treatment: A scoping review

2019

BACKGROUND: While gender-based violence (GBV) has been shown to increase women’s risk of HIV acquisition, the role of GBV in the HIV testing to care continuum is less clear. Clarifying...

Technology-delivered psychotherapeutic interventions in improving depressive symptoms among people with HIV/AIDS: A systematic review and meta-analysis of randomised controlled trials

2019

With the increasing popularity of advanced technology, technology-delivered psychotherapeutic interventions (TPIs) may play a promising role in improving depressive symptoms among PLWHA. However, its effectiveness remains unclear. We aimed to...

Infant feeding practices of HIV positive mothers and its association with counseling and HIV disclosure status in Ethiopia: A systematic review and meta-analysis

2019

Introduction: Breastfeeding is the ideal food source for all newborns globally. However, in the era of Human Immune Deficiency Virus (HIV) infection, feeding practice is a challenge due to mother-to-child...

Late presentation of HIV positive adults and its predictors to HIV/AIDS care in Ethiopia: A systematic review and meta-analysis

2019

INTRODUCTION: Late presentation to HIV/AIDS care which is attended by problems like, poor treatment outcomes, early development of opportunistic infections, increased healthcare costs, and mortality is a major problem in...

Immunological efficacy of Tenofovir disproxil fumarate-containing regimens in Patients With HIV-HBV coinfection: A systematic review and meta-analysis

2019

Background: Hepatitis B virus (HBV) coinfection is common in HIV-positive patients. HIV infection modifies the natural course of HBV infection, leading to a faster progression of liver-related morbidity and mortality...

Voluntary medical male circumcision and HIV infection among men who have sex with men: Implications from a systematic review

2019

Background: With the rapidly-increased HIV epidemic among men who have sex with men worldwide, the effectiveness of voluntary medical male circumcision as the tool of HIV prevention still remains undetermined....

The effect of disclosure on adherence to antiretroviral therapy among adults living with HIV in Ethiopia: A systematic review and meta-analysis

2019

BACKGROUND: Several factors have been identified as being associated with increased adherence to antiretroviral therapy, including sero-status disclosure; however, studies examining the effect of disclosure on ART adherence in Ethiopia...

Risk factors for infectious diseases in urban environments of sub-Saharan Africa: A systematic review and critical appraisal of evidence

2019

Our world is rapidly urbanizing. According to the United Nations, between 1990 and 2015, the percent of the world’s population living in urban areas grew from 43% to 54%. Estimates...

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