Category Archives: Prevention, Engagement and Care Cascade

Impact of male circumcision on risk of HIV infection in men in a changing epidemic context — Systematic review and meta-analysis

2020

INTRODUCTION: WHO/UNAIDS recommended Voluntary Medical Male Circumcision in 2007 based on systematic review of observational studies prior to 1999 and three randomized controlled trials (RCTs). To inform updated WHO guidance,...

Oral pre-exposure prophylaxis (PrEP) continuation, measurement, and reporting: A systematic review and meta-analysis

2020

OBJECTIVE: To appropriately plan for rollout and monitor impact of oral pre-exposure prophylaxis (PrEP) it is important to understand PrEP continuation and come to a consensus on how best to...

Treating progressive disseminated histoplasmosis in people living with HIV

2020

BACKGROUND: Progressive disseminated histoplasmosis (PDH) is a serious fungal infection that affects people living with HIV. The best way to treat the condition is unclear. OBJECTIVES: We assessed evidence in...

Evidence on factors influencing contraceptive use and sexual behavior among women in South Africa: A scoping review

2020

INTRODUCTION: Contraceptive use and sexual health behavior remain a prominent public health concern in South Africa (SA). Despite many government interventions, unintended pregnancies and termination of pregnancies remain relatively high....

Role of vitamin-D supplementation in TB/HIV co-infected patients

2020

Objective: This review aimed to assess the role of vitamin D supplementation on the decrement of mortality and morbidity rate among tuberculosis (TB)/human immune deficiency virus (HIV) co-infected clients.Method: Pub...

Systematic review and meta-analysis of immune response of double dose of hepatitis B vaccination in HIV-infected patients

2020

INTRODUCTION: The prevalence of co-infection of hepatitis B virus (HBV) and human immunodeficiency virus (HIV) is high and increases risk of hepatitis B chronicity and mortality. Despite guidelines for HIV-infected...

Two’s a company, three’s a crowd: A review of initiating or switching to a two-drug antiretroviral regimen in treatment-naive and treatment-experienced patients living with HIV-1

2020

INTRODUCTION: As HIV has become a manageable chronic condition, a renewed and increased interest in challenging traditional three-drug HIV therapies and moving toward two-drug regimens (2DR) for initial or maintenance...

Therapeutic use of cannabis and cannabinoids: An evidence mapping and appraisal of systematic reviews

2020

BACKGROUND: Although cannabis and cannabinoids are widely used with therapeutic purposes, their claimed efficacy is highly controversial. For this reason, medical cannabis use is a broad field of research that...

Verification of HIV self-testing use and results: A global systematic review

2020

HIV self-testing (HIVST) allows individuals to interpret and report their own test results, thus decentralizing testing. Yet, this decentralization can make it difficult to verify self-testing results, which is important...

Mobile health promotion of human immunodeficiency virus self-testing in the United States

2020

Background: Human immunodeficiency virus (HIV) self-testing could overcome barriers associated with traditional HIV testing and increase people’s awareness of their serostatus. Mobile health, which utilizes mobile wireless technology, could alleviate...

The costs of home-based HIV testing and counselling in sub-Saharan Africa and its association with testing yield: A literature review

2019

More than 14.5 of the 36.7 million people living with HIV globally do not know their HIV status, making comprehensive testing interventions a critical step in ending the HIV/AIDS epidemic....

Antiretroviral therapy and the risk of sexual transmission of HIV: A systematic review and meta-analysis

2020

OBJECTIVES: The aim of this study was to evaluate the effect of antiretroviral therapy (ART) with or without condom use on the risk of sexual transmission of HIV. METHODS: A...

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