Category Archives: Prevention, Engagement and Care Cascade

Understanding user perspectives of and preferences for oral PrEP for HIV prevention in the context of intervention scale-up: A synthesis of evidence from sub-Saharan Africa

2019

INTRODUCTION: Oral pre-exposure prophylaxis (PrEP) for HIV prevention has been proven to significantly reduce new HIV infections yet scale-up has been slow. As contexts continue to adjust to make space...

Are policy initiatives aligned to meet UNAIDS 90-90-90 targets impacting HIV testing and linkages to care? Evidence from a systematic review

2019

Background: The Joint United Nations Programme on HIV/AIDS (UNAIDS) Fast-Track initiative seeks to eliminate AIDS as a health threat by 2030, with its focus on UNAIDS 90-90-90 targets. Effective policies and...

Out-of-pocket costs associated with HIV in publicly funded high-income health care settings

2019

Key take-home messages The aging of the people living with HIV in care is leading to increased HIV care costs. There is considerable inter-jurisdictional heterogeneity in the cost-sharing policies for...

The effectiveness of demand creation interventions for voluntary male medical circumcision for HIV prevention in sub-Saharan Africa: A mixed methods systematic review

2019

INTRODUCTION: UNAIDS has recommended that in 14 countries across sub-Saharan Africa (SSA), 90% of men aged 10 to 29 years should be circumcised by 2021 to help reduce transmission of...

Recent interventions to improve retention in HIV care and adherence to antiretroviral treatment among adolescents and youth: A systematic review

2019

Adolescents represent a growing proportion of people living with HIV worldwide and the highest risk population group for treatment attrition and AIDS-related mortality. There is an urgent need to design,...

Strategies to link people with undiagnosed HIV infection to HIV testing, care, and prevention services

2019

Key take-home messages A variety of strategies have shown promise for identifying individuals with undiagnosed HIV and engaging them with HIV testing using clinical, community-based, network-based, and self-directed approaches. Various...

Which community-based HIV initiatives are effective in achieving UNAIDS 90-90-90 targets? A systematic review and meta-analysis of evidence (2007-2018)

2019

BACKGROUND: Reaching the Joint United Nations Programme on HIV/AIDS (UNAIDS) 90-90-90 targets to end the HIV epidemic relies on effective interventions that engage untested HIV+ individuals and retain them in...

Patho-immune mechanisms of hypertension in HIV: A systematic and thematic review

2019

PURPOSE OF REVIEW: To systematically review recent findings on the role of immune cell activation in the pathogenesis of hypertension in people living with HIV (PLWH) and compare studies from...

Pre-exposure prophylaxis for HIV prevention in women: Current status and future directions

2019

Pre-exposure prophylaxis (PrEP) is a promising intervention to prevent HIV acquisition, with benefits both to the individual and to population-level health. PrEP is an opportunity to complement ongoing public health...

Crowdsourcing to improve HIV and sexual health outcomes: A scoping review

2019

Purpose of review: This review synthesizes evidence on the use of crowdsourcing to improve HIV/sexual health outcomes. Recent findings: We identified 15 studies, including four completed randomized controlled trials (RCTs), one planned...

Suboptimal HIV pre-exposure prophylaxis awareness and willingness to use among women who use drugs in the United States: A systematic review and meta-analysis

2019

In the United States (U.S.), more than 12 million women reported illicit drug use in the past month. Drug use has been linked to increased risk for HIV, but little...

Do quality improvement initiatives improve outcomes for patients in antiretroviral programs in low- and middle-income countries? A systematic review

2019

Background: There have been a range of quality improvement (QI) and quality assurance initiatives in low- and middle-income countries to improve antiretroviral therapy (ART) treatment outcomes for people living with HIV....

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