Category Archives: Prevention, Engagement and Care Cascade
Systematic mapping of relationship-level protective factors and sexual health outcomes among sexual minority youth: The role of peers, parents, partners, and providers
Sexual minority youth (SMY) experience elevated rates of adverse sexual health outcomes. Although risk factors driving these outcomes are well studied, less attention has been paid to protective factors that...
Cardiovascular disease in the setting of human immunodeficiency virus infection
BACKGROUND: Since the introduction of Antiretroviral Therapy (ART), the life expectancy and health quality for patients infected with Human Immunodeficiency Virus (HIV) have significantly improved. Nevertheless, as a result of...
Screening for HIV and linkage to care in adolescents: Insights from a systematic review of recent interventions in high- versus low- and middle-income settings
Introduction: Compared to adults, adolescents and young adults have a higher incidence of HIV infection, yet lower rates of HIV testing. Few evidence-based interventions effectively diagnose new HIV infections among...
Comparison of the predictive performance of adherence measures for virologic failure detection in people living with HIV: A systematic review and pairwise meta-analysis
A critical feature of an adherence assessment tool is its ability to predict virologic failure in people living with HIV (PLHIV). We, therefore, aimed to compare the predictive performance of...
Evolving models and ongoing challenges for HIV preexposure prophylaxis implementation in the United States
BACKGROUND: The use of preexposure prophylaxis (PrEP) for HIV prevention was approved by the Food and Drug Administration in 2012, but delivery to at-risk persons has lagged. This critical review...
Progressive disseminated histoplasmosis in Latin America and the Caribbean in people receiving highly active antiretroviral therapy for HIV infection: A systematic review
Histoplasmosis is the most clinically significant mycosis in Latin America; still it has been neglected in people with human immunodeficiency virus (HIV). There is limited information about its contribution to...
A narrative review of internet use, interpersonal connectedness, and sexual behaviour among gay, bisexual and other men who have sex with men
Researchers have often considered the impact that online dating has had on gay communities; with some arguing that changes in social behavior may impact the spread of HIV. However, these...
Chemsex behaviours among men who have sex with men: A systematic review of the literature
BACKGROUND: ‘Chemsex’ is the use of drugs before or during planned sexual events to facilitate, enhance, prolong and sustain the experience. Drugs associated with chemsex are methamphetamine, GHB/GBL, mephedrone, cocaine...
Postpartum women living with HIV: Challenges related to retention in care, treatment adherence, and mental health
Key take-home messages Postpartum women living with HIV may find it challenging to remain engaged in HIV care and achieve optimal adherence to antiretroviral medications. Late entry or suboptimal engagement...
HIV, depression, and cognitive impairment in the era of effective antiretroviral therapy
PURPOSE OF REVIEW: Mental health disorders, especially depression, are prevalent among people living with HIV (PLWH) and are associated with cognitive impairment (CI) among HIV-uninfected (HIV-) individuals. We conducted a...
Atrial fibrillation and human immunodeficiency virus type-1 infection: A systematic review. Implications for anticoagulant and antiarrhythmic therapy
The prevalence and incidence of atrial fibrillation/flutter (AF/AFL) in patients with human immunodeficiency virus type-1 (HIV-1) infection have been poorly investigated. We performed a systematic review using PubMed and Cochrane...
Content guidance for mobile phones short message service (SMS)-based antiretroviral therapy adherence and appointment reminders: A review of the literature
Mobile phones are increasingly being used to support health activities, including the care and management of people living with HIV/AIDS. Short message service (SMS) has been explored as a means...
