Category Archives: Prevention, Engagement and Care Cascade

Adherence to HIV post-exposure prophylaxis for children/adolescents who have been sexually assaulted: A systematic review of barriers, enablers, and interventions

2019

Post-exposure prophylaxis (PEP) is a key intervention for preventing HIV acquisition, including following sexual assault. However, uptake and completion rates for HIV PEP are lowest following sexual assault, with only...

Interventions to reduce gender-based violence among young people living with or affected by HIV/AIDS in low-income and middle-income countries

2019

OBJECTIVE(S): This study explored the effectiveness of gender-based violence (GBV) interventions on young people living with or affected by HIV in low- and middle-income countries (LMICs). DESIGN: Systematic review and...

Peer-led self-management Interventions and adherence to antiretroviral therapy among people living with HIV: A systematic review

2019

Adherence to antiretroviral therapy (ART) is essential to reduce morbidity and mortality among people living with HIV (PLWH). However, adherence remains suboptimal, and PLWH may benefit from more self-management support...

Dolutegravir based antiretroviral therapy compared to other combined antiretroviral regimens for the treatment of HIV-infected naive patients: A systematic review and meta-analysis

2019

BACKGROUND: Numerous randomized clinical trials (RCTs) were conducted to evaluate dolutegravir based triple antiretroviral therapy (ART) compared to other triple antiretroviral regimens in naive patients, and a summary of the...

Getting youth PrEPared: Adolescent consent laws and implications for the availability of PrEP among youth in countries outside of the United States

2019

INTRODUCTION: Youth under the age of 25 are at high risk for HIV infection. While pre-exposure prophylaxis (PrEP) has the potential to curb new infections within this population, it is...

Barriers to the use of mobile health in improving health outcomes in developing countries: Systematic review

2019

BACKGROUND: The use of mobile health (mHealth) technologies to improve population-level health outcomes around the world has surged in the last decade. Research supports the use of mHealth apps to...

Attrition of HIV-positive children from HIV services in low- and middle-income countries: A systematic review and meta-analysis

2019

INTRODUCTION: Identification and retention of HIV-positive children in HIV services is essential to ensure optimal health outcomes. This systematic review and meta-analysis examines the magnitude of attrition (loss to follow-up...

Positive affect and medication adherence in chronic conditions: A systematic review

2019

OBJECTIVE: This review aims to inform research and clinical care on the current state of knowledge on the relationship between positive affect and medication adherence. METHOD: Searches were carried out...

Definition of immunological non-response to antiretroviral therapy: A systematic review

2019

BACKGROUND: Terms and criteria to classify people living with HIV on antiretroviral therapy (ART) who fail to achieve satisfactory CD4 T cell counts are heterogeneous, and need revision and summarization....

Sexually transmitted hepatitis C virus infections: Current trends, and recent advances in understanding the spread in men who have sex with men

2019

INTRODUCTION: Hepatitis C virus (HCV) is a major public health threat. Although the recent availability of highly effective directly acting antivirals created optimism towards HCV elimination, there is ongoing transmission...

Gender-based violence and engagement in biomedical HIV prevention, care and treatment: A scoping review

2019

BACKGROUND: While gender-based violence (GBV) has been shown to increase women’s risk of HIV acquisition, the role of GBV in the HIV testing to care continuum is less clear. Clarifying...

Technology-delivered psychotherapeutic interventions in improving depressive symptoms among people with HIV/AIDS: A systematic review and meta-analysis of randomised controlled trials

2019

With the increasing popularity of advanced technology, technology-delivered psychotherapeutic interventions (TPIs) may play a promising role in improving depressive symptoms among PLWHA. However, its effectiveness remains unclear. We aimed to...

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