Category Archives: Prevention, Engagement and Care Cascade

Effectiveness of digital health interventions in promoting the pre-exposure prophylaxis (PrEP) care continuum among men who have sex with men (MSM): A systematic review of randomized controlled trials

2025

PURPOSE OF REVIEW: Digital health interventions have demonstrated great potential to advance HIV prevention and care. However, their effectiveness in improving the pre-exposure prophylaxis (PrEP) care continuum has not yet...

Improving communication: A narrative synthesis of interventions for HIV disclosure to pediatric populations

2025

PURPOSE OF REVIEW: HIV remains a significant global public health concern, affecting millions worldwide, including children. Disclosure of HIV status to infected children holds several benefits, yet rates of disclosure...

A systematic literature review on pre-exposure prophylaxis as a strategy for HIV risk reduction in the Middle East

2025

Pre-exposure prophylaxis (PrEP) has emerged as a crucial tool in HIV prevention globally, yet its implementation in the Middle East and North Africa (MENA) region faces unique challenges. PrEP is...

Gastrointestinal Escherichia coli in men who have sex with men: A systematic review

2024

OBJECTIVE: This systematic review aimed to explore any demographic, biological and behavioural characteristics of men who have sex with men (MSM) with diarrhoeagenic E.coli. DESIGN/METHODS: We searched MEDLINE, EMBASE, and...

Gender-based violence syndemics in global health: A systematic review

2025

Global guidance indicates that protections for gender and equity issues, such as gender-based violence (GBV), should be mainstreamed across sectors. One novel strategy that can be leveraged to illustrate the...

Four decades of overdose prevention centres: Lessons for the future from a realist review

2025

BACKGROUND: Overdose prevention centres (OPCs) are spaces where people can consume previously obtained illicit drugs under the supervision of staff who can intervene to prevent and manage overdose.AÿThey have been...

Clinical trials of broadly neutralizing monoclonal antibodies in people living with HIV—A review

2025

Introduction HIV-1 remains a major global health challenge, impacting approximately 39 million people worldwide. Although antiretroviral therapy has substantially reduced HIV incidence and enhanced the quality of life for those living...

Experiences of older people living with human immunodeficiency virus comorbidity attending coordinated healthcare services

2025

BACKGROUND: Older people living with human immunodeficiency virus (OPLWHIV) on antiretroviral therapy are aging and face an increased risk of non-communicable diseases. The burden is costly and demands sustainable care...

The role of digital tools in enhancing antiretroviral therapy adherence among adolescents and young adults with HIV: A systematic review of randomized controlled trials

2025

Background: Adolescents and Young Adults (AYA) face challenges in maintaining antiretroviral therapy (ART) adherence, necessitating the need for targeted and innovative interventions. Digital tools have shown potential in improving ART adherence...

Insights into gastrointestinal manifestation of human immunodeficiency virus: A narrative review

2025

Human immunodeficiency virus (HIV) modifies CD4-positive cells, resulting in immunodeficiency and a wide range of gastrointestinal (GI) manifestations. The burden of HIV-related GI illnesses has significantly evolved with the widespread...

Global, regional, and national estimates of hepatitis C virus (HCV) infection incidence among people who inject drugs and number of new annual HCV infections attributable to injecting drug use: A multi-stage analysis

2025

Background: Measuring progress towards the WHO 2030 target for hepatitis C virus (HCV) elimination among people who inject drugs (PWID)-an incidence of two or fewer infections per 100 person-years-has been challenging...

An international compendium of health state utilities in people with HIV: A systematic review

2025

Purpose: Measuring health-related quality of life across different health states for people with HIV (PWH) using direct or indirect preference-based values can inform decision-analytic models evaluating cost-effectiveness of different care strategies....

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