Category Archives: Prevention, Engagement and Care Cascade

Engaging law enforcement in harm reduction programs for people who inject drugs

2016

Key take-home messages Injection drug use is a major contributor to the spread of HIV and Hepatitis C in Canada. Laws and policing practices that govern injection drug use influence...

A systematic evaluation of mobile apps to improve the uptake of and adherence to HIV pre-exposure prophylaxis

2018

Background: Pre-exposure prophylaxis, or PrEP, has been shown to be effective at reducing the risk of HIV infection, yet persons at-risk for acquiring HIV exhibit suboptimal uptake of and adherence...

eHealth literacy in people living with HIV: Systematic review

2018

BACKGROUND: In the era of eHealth, eHealth literacy is emerging as a key concept to promote self-management of chronic conditions such as HIV. However, there is a paucity of research...

Do HIV prevention interventions in Asia lead to increase in condom utilization?: A meta-analysis study

2018

This meta-analytic review synthesizes the findings of published independent studies that assessed the effectiveness of HIV prevention interventions in promoting condom usage in Asia. We focused on 20 studies that...

Cost-effectiveness of front-line services (Updated 2010)

2010

Key take-home messages There is no one-size-fits-all cost-effective HIV strategy. An intervention that is found to be effective at preventing HIV infection has a good chance of being cost-effective due...

Sex worker HIV risk

2012

Key take-home messages The Canadian literature primarily encompasses female sex workers in Vancouver, and studies from other high income countries often addressed demographic niches that were not transferrable to the...

Motivational interviewing

2014

Key tale-home messages Interventions that make use of motivational interviewing can be effective in changing risk behaviours for people living with HIV; the longer the motivational interviewing intervention, the more...

Impact of childhood sexual abuse on antiretroviral medication adherence, sexual risk behaviours and overall health among men who have sex with men

2016

Key take-home messages Men who have sex with men are two to four times more likely than men in the general population to have experienced childhood sexual abuse. Men who...

Quality of HIV websites with information about pre-exposure prophylaxis or treatment as prevention for men who have sex with men: A systematic evaluation

2018

BACKGROUND: Knowledge and uptake of high-efficacy HIV prevention strategies such as pre-exposure prophylaxis (PrEP) and treatment as prevention (TasP) remain low among men who have sex with men (MSM) who...

Lamivudine plus tenofovir combination therapy versus lamivudine monotherapy for HBV/HIV coinfection: A meta-analysis

2018

BACKGROUND: Currently, there is no consensus on the efficacy and safety of lamivudine (LAM) plus tenofovir disoproxil fumarate (TDF) combination therapy versus lamivudine monotherapy in HBV/HIV coinfected patients. METHODS: A...

Individual patient data meta-analysis of randomized controlled trials of dual therapy with a boosted PI plus lamivudine for maintenance of virological suppression: GeSIDA study 9717

2018

Background: Dual therapy (DT) with a ritonavir-boosted PI (PI/r) plus lamivudine has proven non-inferior (12% margin) to triple therapy (TT) with PI/r plus two nucleos(t)ide reverse transcriptase inhibitors [N(t)RTIs] in...

Effectiveness and impact of using the internet for prevention of HIV/AIDS

2009

Key take-home messages The Internet is a feasible channel to deliver HIV prevention and intervention. With the internet increasingly used not only for meeting sex partners but also for finding...

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