Category Archives: Prevention, Engagement and Care Cascade
Assessing the efficacy of lopinavir/ritonavir-based preferred and alternative second-line regimens in HIV-infected patients: A meta-analysis of key evidence to support WHO recommendations
Background: Nucleoside reverse transcriptase inhibitors (NRTIs) and non-NRTIs (NNRTIs) with boosted protease inhibitors are included in standardized first-line and second-line regimens. Recent World Health Organization (WHO) guidelines recommend a boosted...
Is alcohol use associated with increased risk of developing adverse health outcomes among adults living with human immunodeficiency virus: A systematic review
BACKGROUND: Alcohol use is associated with many HIV-related behaviors that are associated with increased risk of reinfection, transmission, and poorer health outcomes in people living with HIV (PLHIV). The population...
A review of approaches used to increase awareness of pre-exposure prophylaxis (PrEP) in the United States
PrEP is an important and useful HIV prevention strategy, yet awareness remains low among at-risk populations in the United States and elsewhere in the world. As previous studies have shown...
Implementation of eHealth interventions across the HIV care cascade: A review of recent research
PURPOSE OF REVIEW: We review recent implementation science focusing on eHealth interventions to improve outcomes along the HIV care cascade. We highlight several gaps in the eHealth implementation literature and...
Effectiveness and cost-effectiveness of pre- & post-exposure prophylaxis for HIV
Key take-home messages There is not enough evidence to draw conclusions about the clinical effectiveness of non-occupational post-exposure prophylaxis (PEP); however, non-occupational PEP is possibly a cost-effective intervention. PEP has...
The effects of viral load and antiretroviral medications on sexual transmission of HIV
Key take-home messages Several studies have noted differences in viral load levels when comparing blood plasma to semen, cervicovaginal secretions and rectal mucosa. Despite an undetectable blood plasma viral load...
