Category Archives: Prevention, Engagement and Care Cascade
A systematic review of HIV pre-exposure prophylaxis (PrEP) implementation in U.S. emergency departments: Patient screening, prescribing, and linkage to care
In the pursuit of ending the HIV epidemic, U.S. emergency departments (EDs) have emerged as a valuable setting to increase HIV testing and linkage to care. There is limited data...
Influences affecting decision-making regarding use of pre-exposure prophylaxis among black men who have sex with men in the USA: A systematic review and meta-synthesis
AIM: To systematically identify, evaluate, and synthesise qualitative research examining positive and negative influences affecting decision-making behaviour among black men who have sex with men (BMSM) in the USA regarding...
Fixed-dose antiretroviral combinations in children living with human immunodeficiency virus type 1 (HIV-1): A systematic review
Fixed-Dose antiretroviral Combinations (FDCs) are the most used drug regimes in adult patients with human-immunodeficiency virus 1 infection, since they increase adherence to antiretroviral therapy and enable good quality of...
Non-adherence to anti-retroviral therapy among adult people living with HIV in Ethiopia: Systematic review and meta-analysis
Human immunodeficiency virus remains a global public health problem. Despite efforts to determine the prevalence of non-adherence to ART and its predictors in Ethiopia, various primary studies presented inconsistent findings....
Adverse effects of daily oral pre-exposure prophylaxis in men who have sex with men and transgender women: A systematic review and meta-analysis
The adverse effects of oral pre-exposure prophylaxis (PrEP) using tenofovir disoproxil fumarate are barriers to PrEP initiation and continuation. Although serious effects are rare and predictable, evidence for this assessment...
A scoping review on HIV early infant diagnosis among HIV exposed infants, ART use and adherence in Tanzania
BACKGROUND: HIV Early Infant Diagnosis (HEID) is critical for the timely initiation of HIV treatments and improved health outcomes among HIV-infected infants. However, the uptake of HEID remains largely low...
Assessing bone mineral density in children and adolescents living with HIV and on treatment with tenofovir disoproxil fumarate: A systematic review
OBJECTIVE: To investigate the impact of tenofovir disoproxil fumarate on bone mineral density and bone mineral content in children and adolescents infected with the human immunodeficiency virus. DATA SOURCE: The...
Demand creation and retention strategies for oral pre-exposure prophylaxis for HIV prevention among men who have sex with men and transgender women: A systematic review and meta-analysis
Background Men who have sex with men (MSM) and transgender women (TGW) have a disproportionately higher risk of human immunodeficiency virus (HIV) infection than other groups. Oral HIV pre-exposure prophylaxis...
Non-pharmacological interventions for improving sleep in people living with HIV: A systematic narrative review
BACKGROUND: Sleep disturbances are common in people living with Human Immunodeficiency Virus (HIV) and may lead to poor adherence to antiretroviral therapy and worsen HIV symptom severity. Due to the...
Statistical methods applied for the assessment of the HIV cascade and continuum of care: A systematic scoping review
OBJECTIVES: This scoping review aims to identify and synthesise existing statistical methods used to assess the progress of HIV treatment programmes in terms of the HIV cascade and continuum of...
Barriers and facilitators for interventions to improve ART adherence in Sub-Saharan African countries: A systematic review and meta-analysis
BACKGROUND: The HIV/AIDS pandemic remains a significant public health issue, with sub-Saharan Africa (SSA) at its epicentre. Although antiretroviral therapy (ART) has been introduced to decrease new infections and deaths,...
