Category Archives: Prevention, Engagement and Care Cascade
Statistical methods applied for the assessment of the HIV cascade and continuum of care: A systematic scoping review
OBJECTIVES: This scoping review aims to identify and synthesise existing statistical methods used to assess the progress of HIV treatment programmes in terms of the HIV cascade and continuum of...
Barriers and facilitators for interventions to improve ART adherence in Sub-Saharan African countries: A systematic review and meta-analysis
BACKGROUND: The HIV/AIDS pandemic remains a significant public health issue, with sub-Saharan Africa (SSA) at its epicentre. Although antiretroviral therapy (ART) has been introduced to decrease new infections and deaths,...
The association of women’s empowerment with HIV-related indicators: A pooled analysis of demographic and health surveys in sub-Saharan Africa
Background Women’s empowerment is an important factor for HIV prevention, but the association with HIV-related indicators has never been quantified. In this study, we examined the association between women’s empowerment...
Pharmacological and behavioral interventions to mitigate premature aging in patients with HIV
PURPOSE OF REVIEW: We sought to review pharmacological and behavioral interventions that have been publicly presented, published, or are currently ongoing to prevent or mitigate the effect of premature HIV-associated...
Global, regional, and country-level coverage of testing and treatment for HIV and hepatitis C infection among people who inject drugs: A systematic review
Background People who inject drugs are disproportionately affected by HIV and hepatitis C virus (HCV) infections, while there is little global data on HIV and HCV testing and treatment coverage...
Pre-exposure prophylaxis care continuum for HIV risk populations: An umbrella review of systematic reviews and meta-analyses
Pre-exposure prophylaxis (PrEP) is an effective biomedical strategy for HIV prevention. This umbrella review is aimed at providing a comprehensive summary of the current status of each stage of the...
Recent progress in synthesis, POM analyses and SAR of Coumarin-hybrids as potential anti-HIV agents—A Mini Review
The human immunodeficiency virus (HIV) is the primary cause of acquired immune deficiency syndrome (AIDS), one of the deadliest pandemic diseases. Various mechanisms and procedures have been pursued to synthesise...
Machine learning prediction models for clinical management of blood-borne viral infections: A systematic review of current applications and future impact
BACKGROUND: Machine learning (ML) prediction models to support clinical management of blood-borne viral infections are becoming increasingly abundant in medical literature, with a number of competing models being developed for...
Adherence to antiretroviral therapy among HIV patients in Ghana: A systematic review and meta-analysis
Maintaining a high level of adherence to antiretroviral therapy (ART) is critical to limiting rapid viral replication, drug resistance, and viral transmission. However, ART adherence remains a major challenge in...
Virologic response to Dolutegravir plus Lamivudine in people with suppressed human immunodeficiency virus type 1 and historical M184V/I: A systematic literature review and meta-analysis
BACKGROUND: To investigate the impact of the M184V/I mutation on virologic response to dolutegravir plus lamivudine (DTG + 3TC) in suppressed-switch populations, a meta-analysis was performed using virologic outcomes from...
Health facility-based interventions and the uptake of contraception among people living with HIV: A systematic review & meta-analysis
BACKGROUND OBJECTIVES: The prong 2 of 4 prong strategy introduced by the World Health Organization aims at averting unintended pregnancies among people living with HIV (PLHIV). This systematic review aimed...
