Category Archives: Prevention, Engagement and Care Cascade

Do you PrEP? A review of primary care provider knowledge of PrEP and attitudes on prescribing PrEP

2018

Oral preexposure prophylaxis (PrEP) has been proven to be a safe and effective means of preventing HIV. The purpose of our literature review was to examine primary care provider knowledge...

A meta-analysis of HIV postexposure prophylaxis among sexually assaulted patients in the United States

2018

Sexual assault (SA) is a major public health problem that leaves patients at risk for HIV. The gold standard of medical treatment for SA patients includes prophylactic treatment to prevent...

It’s not just the pills: A qualitative meta-synthesis of HIV antiretroviral adherence research

2017

Antiretroviral therapy (ART) improves the health and longevity of people living with HIV infection (PLWH) and also prevents transmission of the virus. Yet, lack of adherence to ART regimens has...

Effectiveness of protease inhibitor/nucleos(t)ide reverse transcriptase inhibitor-based second-line antiretroviral therapy for the treatment of HIV-1 infection in sub-Saharan Africa: Systematic review and meta-analysis

2017

Background: In sub-Saharan Africa, 25.5 million people are living with HIV, representing 70% of the global total. The need for second-line antiretroviral therapy (ART) is projected to increase in the...

Cost-effectiveness of routine viral load monitoring in low- and middle-income countries: A systematic review

2017

INTRODUCTION: Routine viral load monitoring for HIV-1 management of persons on antiretroviral therapy (ART) has been recommended by the World Health Organization (WHO) to identify treatment failure. However, viral load...

Health literacy for people living with HIV/Aids: An integrative review

2017

Objective:: to analyze knowledge produced by research about health literacy for adult with HIV/Aids. Method:: an integrative literature review, using six databases, was conducted between January and April of 2014....

Most common oral manifestations in pediatric patients HIV positive and the effect of highly active antiretroviral therapy

2018

This integrative literature review aims to identify the main oral lesions affecting pediatric patients with HIV, and describe the effect of highly active antiretroviral therapy (HAART) on these injuries, comparing...

Interventions to significantly improve service uptake and retention of HIV-positive pregnant women and HIV-exposed infants along the prevention of mother-to-child transmission continuum of care: Systematic review

2018

OBJECTIVES: Despite the success of Prevention of Mother-to-Child Transmission of HIV (PMTCT) programmes, low uptake of services and poor retention pose a formidable challenge to achieving the elimination of vertical...

HIV risk inside U.S. prisons: A systematic review of risk reduction interventions conducted in U.S. prisons

2017

HIV prevalence in correctional populations is approximately five times that of the general adult population. This systematic review examines the broad question of HIV prevention and interventions to reduce inmate...

CD4 count and tuberculosis risk in HIV-positive adults not on ART: A systematic review and meta-analysis

2017

Background: CD4 cell count in adults with human immunodeficiency virus (HIV) infection (PLHIV) not receiving antiretroviral therapy (ART) influences tuberculosis (TB) risk. Despite widespread use in models informing resource allocation,...

Reduced bone mineral density in human immunodeficiency virus-infected individuals: A meta-analysis of its prevalence and risk factors

2017

A meta-analysis was conducted to evaluate the prevalence of osteopenia/osteoporosis in human immunodeficiency virus (HIV)-infected individuals. The prevalence of osteopenia/osteoporosis in HIV-infected and antiretroviral therapy (ART)-treated individuals was significantly higher...

Tenofovir disoproxil fumarate safety for women and their infants during pregnancy and breastfeeding

2017

OBJECTIVES: Pregnant/lactating women in some sub-Saharan Africa settings are at substantial risk of HIV acquisition and could benefit from preexposure prophylaxis (PrEP) with tenofovir disoproxil fumarate (TDF), but safety data...

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