Category Archives: Prevention, Engagement and Care Cascade

Clinical and public health implications of acute and early HIV detection and treatment: A scoping review

2017

INTRODUCTION: The unchanged global HIV incidence may be related to ignoring acute HIV infection (AHI). This scoping review examines diagnostic, clinical, and public health implications of identifying and treating persons...

Reliability of white matter microstructural changes in HIV infection: Meta-analysis and confirmation

2017

BACKGROUND: Diffusion tensor imaging has been widely used to measure HIV effects on white matter microarchitecture. While many authors have reported reduced fractional anisotropy and increased mean diffusivity in HIV,...

Micronutrient supplementation in adults with HIV infection

2017

BACKGROUND: Micronutrient deficiencies are common among adults living with HIV disease, particularly in low-income settings where the diet may be low in essential vitamins and minerals. Some micronutrients play critical...

Critical review: What dose of rifabutin is recommended with antiretroviral therapy?

2016

Since the advent of combination antiretroviral therapy to successfully treat HIV infection, drug-drug interactions (DDIs) have become a significant problem as many antiretrovirals (ARVs) are metabolized in the liver. Antituberculous...

Global prevalence of hypertension among people living with HIV: A systematic review and meta-analysis

2017

The purpose of this study was to estimate, through meta-analysis, the global prevalence of hypertension among people living with HIV (PLWH). A total of 49 studies published during 2011-2016 with...

Determinants of adherence to antiretroviral therapy among HIV-positive adults in sub-Saharan Africa: A systematic review

2016

OBJECTIVE: The rapid scale up of antiretroviral treatment (ART) in sub-Saharan Africa (SSA) has resulted in an increased focus on patient adherence. Non-adherence can lead to drug-resistant HIV caused by...

HIV and the criminalisation of drug use among people who inject drugs: A systematic review

2017

BACKGROUND: Mounting evidence suggests that laws and policies prohibiting illegal drug use could have a central role in shaping health outcomes among people who inject drugs (PWID). To date, no...

Is location of sex associated with sexual risk behaviour in men who have sex with men? Systematic review of within-subjects studies

2016

To understand associations between location of sex and sexual risk, it is most helpful to compare sexual encounters within persons. We systematically reviewed within-subjects comparisons of sexual encounters reported by...

Objective impairments of gait and balance in adults living with HIV-1 infection: A systematic review and meta-analysis of observational studies

2017

BACKGROUND: Gait and balance deficits are reported in adults with HIV infection and are associated with reduced quality of life. Current research suggests an increased fall-incidence in this population, with...

HIV-associated executive dysfunction in the era of modern antiretroviral therapy: A systematic review and meta-analysis

2017

OBJECTIVE: While some reports suggest that HIV+ individuals continue to display executive function (EF) impairment in the era of cART, findings have been contradictory and appear to differ based on...

Systematic review and meta-analysis of the adolescent HIV continuum of care in South Africa: the Cresting Wave

2016

CONTEXT: South Africa has the most HIV infections of any country in the world, yet little is known about the adolescent continuum of care from HIV diagnosis through viral suppression....

Web and mobile based HIV prevention and intervention programs pros and cons – A review

2017

BACKGROUND: With the increasing growth of HIV positive people the use of information and communication technologies (ICT) can play an important role in controlling the spread of the AIDS. Web...

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