Category Archives: Prevention, Engagement and Care Cascade

The potential cost-effectiveness of HIV vaccines: A systematic review

2017

OBJECTIVE: The aim of this paper was to review and compare HIV vaccine cost-effectiveness analyses and describe the effects of uncertainty in model, methodology, and parameterization. METHODS: We systematically searched...

Uptake contexts and perceived impacts of HIV testing and counselling among adults in East and Southern Africa: A meta-ethnographic review

2017

INTRODUCTION: HIV testing and counselling (HTC) interventions are key to controlling the HIV epidemic in East and Southern Africa where HTC is primarily delivered through voluntary counselling and testing (VCT),...

Brief interventions to prevent sexually transmitted infections suitable for in-service use: A systematic review

2016

BACKGROUND: Sexually transmitted infections (STIs) are more common in young people and men who have sex with men (MSM) and effective in-service interventions are needed. METHODS: A systematic review of...

Behavioural disinhibition in the general population during the antiretroviral therapy roll-out in Sub-Saharan Africa: Systematic review and meta-analysis

2017

Objectives: Improved life expectancy and reduced transmission probabilities due to ART may result in behavioural disinhibition – that is an increase in sexual risk behaviour in response to a perceived lower...

A systematic review and meta-analysis of psychosocial interventions to reduce drug and sexual blood borne virus risk behaviours among people who inject drugs

2017

Opiate substitution treatment and needle exchanges have reduced blood borne virus (BBV) transmission among people who inject drugs (PWID). Psychosocial interventions could further prevent BBV. A systematic review and meta-analysis...

Healthy aging in older women living with HIV infection: A systematic review of psychosocial factors

2017

Due to life-enhancing effects of antiretroviral therapy, HIV-positive persons have the potential for long life comparable to their uninfected peers. Older women (age 50+) living with HIV (OWLH) are often...

Systematic review of sex work interventions in sub-Saharan Africa: Examining combination prevention approaches

2017

OBJECTIVE: The incidence of HIV and sexually transmitted infections is disproportionately high among sex workers (SW). We aimed to update the evidence on the effectiveness of SW interventions in sub-Saharan...

The promotion of intrauterine contraception in low- and middle-income countries: A narrative review

2017

CONTEXT: The contribution of copper-bearing intrauterine devices (IUDs) to overall contraceptive protection has declined in many countries, despite their well-known advantages. In response, initiatives to promote this method have been...

A global estimate of the acceptability of pre-exposure prophylaxis for HIV among men who have sex with men: A systematic review and meta-analysis

2017

Pre-exposure prophylaxis (PrEP) is a new biomedical intervention for HIV prevention. This study systematically reviews the acceptability of PrEP among men who have sex with men (MSM) worldwide. We searched...

Association between depression and antiretroviral therapy use among people living with HIV: A meta-analysis

2017

Depression is common among people living with HIV (PLHIV). Studies on the relationship between depression and use of antiretroviral therapy (ART) are inconclusive. A meta-analysis was conducted to summarize the...

Postnatal HIV transmission in breastfed infants of HIV-infected women on ART: A systematic review and meta-analysis

2017

INTRODUCTION: To systematically review the literature on mother-to-child transmission in breastfed infants whose mothers received antiretroviral therapy and support the process of updating the World Health Organization infant feeding guidelines...

Enhancing public health HIV interventions: A qualitative meta-synthesis and systematic review of studies to improve linkage to care, adherence, and retention

2017

Although HIV services are expanding, few have reached the scale necessary to support universal viral suppression of individuals living with HIV. The purpose of this systematic review was to summarize...

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