Category Archives: Prevention, Engagement and Care Cascade

A review of transition experiences in perinatally and behaviourally acquired HIV-1 infection; Same, same but different?

2017

INTRODUCTION: Despite sharing common psychosocial and developmental experiences, adolescents living with perinatally and behaviourally acquired HIV-1 infection are different in terms of timing of HIV infection and developmental stage at...

Critical review: Review of the efficacy, safety, and pharmacokinetics of raltegravir in pregnancy

2016

Raltegravir was previously considered an alternative antiretroviral in pregnancy because of limited data, but recent pregnancy guidelines recommend raltegravir as a preferred integrase treatment option. Data from published articles and...

The association between HIV (treatment), pregnancy serum lipid concentrations and pregnancy outcomes: A systematic review

2017

BACKGROUND: Observed adverse effects of antiretroviral therapy (ART) on the lipid profile could be of significance in pregnancy. This systematic review aims to summarize studies that investigated the association between...

HIV risk-reduction prevention interventions targeting African American adolescent women

2016

African American young women are overwhelmingly disproportionately burdened by HIV/AIDS in the United States today. The purpose of the current systematic review was to identify the characteristics of efficacious HIV...

HIV healthcare transition outcomes among youth in North America and Europe: A review

2017

INTRODUCTION: The transition from paediatric to adult care poses risks to the health of young adults living with HIV if unsuccessful, including interruptions in care and poor health outcomes. Evolving...

Clinical outcomes of HIV care delivery models in the US: A systematic review

2016

With over 1 million people living with HIV, the US faces national challenges in HIV care delivery due to an inadequate HIV specialist workforce and the increasing role of non-communicable...

Integrating HIV and substance use services: A systematic review

2017

INTRODUCTION: Substance use is an important risk factor for HIV, with both concentrated in certain vulnerable and marginalized populations. Although their management differs, there may be opportunities to integrate services...

The impact of motivational interviewing on adherence and symptom severity in adolescents and young adults with chronic illness: A systematic review

2017

OBJECTIVE: Given the negative consequences associated with non-adherence in adolescents and young adults (AYAs) with chronic illness, it is important to identify interventions to address this issue. Therefore, this review’s...

Adolescents with HIV and transition to adult care in the Caribbean, Central America and South America, Eastern Europe and Asia and Pacific regions

2017

INTRODUCTION: The HIV epidemics in the Caribbean, Central America and South America (CCASA), Eastern Europe (EE) and Asia and Pacific (AP) regions are diverse epidemics affecting different key populations in...

HIV-free survival at 12-24 months in breastfed infants of HIV-infected women on antiretroviral treatment

2016

OBJECTIVE: To provide estimates of HIV-free survival at 12-24 months in breastfed children by maternal ART (6 months or lifelong) to inform WHO HIV and Infant Feeding guidelines. METHODS: Eighteen...

Awareness and willingness to use HIV pre-exposure prophylaxis among men who have sex with men in low- and middle-income countries: A systematic review and meta-analysis

2017

INTRODUCTION: To facilitate provision of pre-exposure prophylaxis (PrEP) in low- and middle-income countries (LMIC), a better understanding of potential demand and user preferences is required. This review assessed awareness and...

Does maternal HSV-2 coinfection increase mother-to-child transmission of HIV? A systematic review

2017

BACKGROUND: Reducing HIV mother-to-child transmission (MTCT) is critical to ending the HIV pandemic. Reports suggest that herpes simplex virus-2 (HSV-2), a common coinfection in HIV-infected individuals, is associated with increased...

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