Category Archives: Prevention, Engagement and Care Cascade
Brief report: Preventing HIV-1 infection in women using oral preexposure prophylaxis: A meta-analysis of current evidence
The World Health Organization has issued an early release revision to its antiretroviral guidelines in which PrEP (pre-exposure prophylaxis in the form of daily oral, fixed dose combination tenofovir disoproxil...
Pre-exposure prophylaxis for HIV prevention: Safety concerns
Available evidence supports the efficacy of pre-exposure prophylaxis (PrEP) in decreasing the incidence of human immunodeficiency virus (HIV) infection among high-risk individuals, especially when used in combination with other behavioural...
HIV care and treatment experiences among female sex workers living with HIV in sub-Saharan Africa: A systematic review
Female sex workers (FSW) living with HIV in sub-Saharan Africa have poor engagement to HIV care and treatment. Understanding the HIV care and treatment engagement experiences of FSW has important...
Behavioral interventions to promote condom use among women living with HIV: A systematic review update
Behavioral interventions have been essential components of HIV prevention approaches, especially those aimed to promote safe sexual practices. We conducted a comprehensive literature search without language restrictions between 1980 and...
Diagnostic value and safety of stereotactic biopsy in acquired immune deficiency syndrome patients with intracranial lesions: Systematic review and meta-analysis
OBJECTIVE: To evaluate the diagnostic value and safety of stereotactic biopsy in acquired immune deficiency syndrome (AIDS) patients with intracranial lesions via meta-analysis. METHODS: Relevant cohort studies were identified through...
Patient-reported barriers and facilitators to antiretroviral adherence in sub-Saharan Africa: A systematic review
OBJECTIVE: To identify the range and frequency of patient-reported barriers and facilitators to antiretroviral treatment (ART) adherence in Sub-Saharan Africa (SSA). DESIGN: Studies from 2005-2016 were identified by searching 10...
Comparative effectiveness of tenofovir in HIV-infected treatment-experienced patients: Systematic review and meta-analysis
BACKGROUND: Antiretroviral therapy (ART) regimens for HIV infection are frequently changed. We conducted a systematic review of randomized trials (RCTs) on the benefits and harms of switching to tenofovir disoproxil...
Marked sex differences in all-cause mortality on antiretroviral therapy in low- and middle-income countries: A systematic review and meta-analysis
INTRODUCTION: While women and girls are disproportionately at risk of HIV acquisition, particularly in low- and middle-income countries (LMIC), globally men and women comprise similar proportions of people living with...
Challenges in the evaluation of interventions to improve engagement along the HIV care continuum in the United States: A systematic review
In the United States (US), there are high levels of disengagement along the HIV care continuum. We sought to characterize the heterogeneity in research studies and interventions to improve care...
Interferon-free therapies for patients with chronic hepatitis C genotype 3 infection: A systematic review
Treatment of hepatitis C virus (HCV) infection with genotype 3 remains a challenge. The HCV elimination rate with direct-acting antivirals (DAAs) is lower than the values reported for other HCV...
