Category Archives: Prevention, Engagement and Care Cascade
Patient-reported barriers and facilitators to antiretroviral adherence in sub-Saharan Africa: A systematic review
OBJECTIVE: To identify the range and frequency of patient-reported barriers and facilitators to antiretroviral treatment (ART) adherence in Sub-Saharan Africa (SSA). DESIGN: Studies from 2005-2016 were identified by searching 10...
Comparative effectiveness of tenofovir in HIV-infected treatment-experienced patients: Systematic review and meta-analysis
BACKGROUND: Antiretroviral therapy (ART) regimens for HIV infection are frequently changed. We conducted a systematic review of randomized trials (RCTs) on the benefits and harms of switching to tenofovir disoproxil...
Marked sex differences in all-cause mortality on antiretroviral therapy in low- and middle-income countries: A systematic review and meta-analysis
INTRODUCTION: While women and girls are disproportionately at risk of HIV acquisition, particularly in low- and middle-income countries (LMIC), globally men and women comprise similar proportions of people living with...
Challenges in the evaluation of interventions to improve engagement along the HIV care continuum in the United States: A systematic review
In the United States (US), there are high levels of disengagement along the HIV care continuum. We sought to characterize the heterogeneity in research studies and interventions to improve care...
Interferon-free therapies for patients with chronic hepatitis C genotype 3 infection: A systematic review
Treatment of hepatitis C virus (HCV) infection with genotype 3 remains a challenge. The HCV elimination rate with direct-acting antivirals (DAAs) is lower than the values reported for other HCV...
Efficacy of human immunodeficiency virus/sexually transmitted infection prevention interventions targeting female entertainment workers: A systematic review and meta-analysis
Female entertainment workers (FEWs) working in karaoke lounges, bars, pubs, nightclubs, discotheques, dance halls, massage parlours, restaurants (as hostesses or singers) and beer gardens are at high risk for human...
The efficacy and safety of tenofovir alafenamide versus tenofovir disoproxil fumarate in antiretroviral regimens for HIV-1 therapy: Meta-analysis
BACKGROUND: To date, a definite conclusion about efficiency and safety of tenofovir alafenamide for patients with HIV-1 is not available. The aim of the study was to investigate the efficacy...
Adherence to antiretroviral therapy among HIV-infected prisoners: A systematic review and meta-analysis
Data on antiretroviral therapy (ART) adherence among prison inmates are limited and not previously synthesized in a systematic manner. The objective of this study was to provide accurate and up-to-date...
Visual analogue scale (VAS) measurement of antiretroviral adherence in people living with HIV (PLWH): A meta-analysis
Effective treatment of HIV hinges upon maintaining adequate antiretroviral therapy adherence. Accurate, cost-effective measurement of medication adherence is needed to best respond to the HIV pandemic. The visual analogue scale...
Enhancing HIV prevention among young men who have sex with men: A systematic review of HIV behavioral interventions for young gay and bisexual men
Men who have sex with men (MSM) represent 64.0% of people living with HIV (PLWH) over the age of 13 years. Young men who have sex with men (YMSM) are...
