Category Archives: Prevention, Engagement and Care Cascade

Association of HLA-B*5701 genotypes and abacavir-induced hypersensitivity reaction: A systematic review and meta-analysis

2015

OBJECTIVES: This study aimed to systematically review and quantitatively synthesize the association between HLA-B*5701 and abacavir-induced hypersensitivity reaction (ABC-HSR). METHODS: We searched for studies that investigated the association between HLA-B...

A synthesis of meta-analytic evidence of behavioral interventions to reduce HIV/STIs

2016

To identify the mode of delivery, communicator, and content dimensions that make STI/HIV prevention interventions most successful at increasing condom use/protected sex or reducing STI/HIV incidence. A literature search for...

Male partners’ involvement in prevention of mother-to-child HIV transmission in sub-Saharan Africa: A systematic review

2015

In sub-Saharan Africa (SSA), male partners are rarely present during prevention of mother-to-child transmission (PMTCT) services. This systematic review aims to synthesize, from a male perspective, male partners’ perceived roles,...

HIV and sexual risk among men who have sex with men and women in Asia: A systematic review and meta-analysis

2016

We performed a systematic review to estimate the proportion of men who have sex with men (MSM) in Asia who are bisexual and compare prevalence of HIV and sexual risk...

HIV: Prevention of mother-to-child transmission

2011

INTRODUCTION: Over 2 million children are thought to be living with HIV/AIDS worldwide, of whom over 80% live in sub-Saharan Africa. Without antiretroviral treatment, the risk of HIV transmission from...

Incentivizing HIV/STI testing: A systematic review of the literature.

2014

Suboptimal HIV/STI testing uptake has a profound impact on morbidity and mortality. Incentives have been effective in other areas of medicine and may improve HIV/STI testing uptake rates. This study...

Depression and adherence to antiretroviral therapy in low-, middle- and high-income countries: A systematic review and meta-analysis

2014

We investigated the associations between depressive symptoms and adherence to antiretroviral therapy (ART) among people living with HIV (PLHIV). We searched the PubMed, EMBASE and Cochrane CENTRAL databases for studies...

Optimal strategies for monitoring response to antiretroviral therapy in HIV-infected adults, adolescents, children and pregnant women: A systematic review

2014

OBJECTIVE: The objective of this review was to examine different monitoring strategies (clinical, immunologic (CD4 T cell count measurement) and virologic (viral load measurement)) to inform revision of the 2013...

Systematic review of HIV drug resistance in Southeast Asia

2013

In 2010, 3.5 million people were living with HIV in the World Health Organization Southeast Asia Region (SEAR), giving this region the greatest burden of HIV after Africa. Scale-up of...

Factors associated with adherence to antiretroviral therapy among adolescents living with HIV/AIDS in low- and middle-income countries: A systematic review

2015

Adolescents living in low- and middle-income countries (LMICs) are disproportionately burdened by the global HIV/AIDS pandemic. Maintaining medication adherence is vital to ensuring that adolescents living with HIV/AIDS receive the...

Predicting treatment failure in adults and children on antiretroviral therapy: A systematic review of the performance characteristics of the 2010 WHO immunologic and clinical criteria for virologic failure

2014

OBJECTIVE: We systematically reviewed the performance of 2010 WHO immunologic and clinical criteria for predicting virologic failure in HIV-infected patients on antiretroviral therapy (ART). DESIGN: Systematic review. METHODS: We used...

Choice of antiretroviral drugs for postexposure prophylaxis for children: A systematic review

2015

BACKGROUND: This systematic review aimed to assess the safety and efficacy of antiretroviral options for postexposure prophylaxis (PEP). Recognizing the limited data on the safety and efficacy of antiretroviral drugs...

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