Category Archives: Prevention, Engagement and Care Cascade
Ambivalent experiences of people in treatment for tuberculosis-HIV coinfection: A meta-synthesis of qualitative studies
This study examined the scientific literature, by means of a systematic review with meta-synthesis (PROSPERO No. CRD42023410141), to discover the experiences of people undergoing treatment for tuberculosis-HIV coinfection. Ten databases...
Interventions to improve HIV care continuum outcomes for people with HIV who have incarceration experience: A narrative review
People with HIV who are reentering the community after incarceration encounter multiple barriers to engagement in HIV care and treatment. We conducted a narrative review of recent interventions (2020-2023) developed...
How do migrants living with HIV adhere to the HIV care process in high-income countries? A systematic review
BACKGROUND: In high-income countries (HICs), migrants living with HIV (MLHIV) are more likely than other HIV subpopulations to encounter problems which hamper their adherence to the care process; these include...
HIV post-exposure prophylaxis in community settings and by lay health workers or through task sharing: A systematic review of effectiveness, case studies, values and preferences, and costs
INTRODUCTION: Post-exposure prophylaxis (PEP) for HIV prevention has been inadequately promoted, provided and used. Expanded access and task sharing could increase the HIV prevention impact of PEP, but scientific evidence...
User preferences on long-acting pre-exposure prophylaxis for HIV prevention in Eastern and Southern Africa: A scoping review
BACKGROUND: Novel formulations for pre-exposure prophylaxis (PrEP) such as injectables, implants, and intravaginal rings are emerging as long-acting alternatives to daily pills for the prevention of HIV. Eastern and Southern...
Vending machines for reducing harm associated with substance use and use disorders, and co-occurring conditions: A systematic review
Background To stem rising fatal overdoses and other substance use/use disorder (SUD)-related harms, communities are turning to low-barrier harm reduction strategies, such as harm reduction-focused vending machines (VMs) that distribute...
Characterization and stratification of risk factors of stroke in people living with HIV: A theory-informed systematic review
Background Identification and stratification of risk factors for stroke among individuals living with HIV (PLWH) will facilitate primary prevention and prognostication, as well as strategies aimed at optimizing neurorehabilitation. This...
Knowledge, attitudes, and willingness of healthcare workers to offer pre-exposure prophylaxis in Africa: A systematic review and meta-analysis
Background Despite advancements in HIV prevention strategies, including pre-exposure prophylaxis (PrEP), uptake remains suboptimal in high-burden regions like Africa. Healthcare workers (HCWs) play a pivotal role in PrEP implementation. This...
Morbidity and mortality risk among people with HIV and central or visceral adiposity: A targeted literature review
BACKGROUND: Given the known relationship between human immunodeficiency virus (HIV), antiretroviral therapies, and excess visceral adipose tissue (VAT), this review sought to characterize risk of negative health outcomes associated with...
Mental health interventions for young pepole living with HIV/AIDS in sub-Saharan Africa: A systematic review
Introduction: Young people (aged 15-24) living with HIV/AIDS (YPLHIV) in sub-Saharan Africa (SSA) experience higher rates of mental health conditions compared to their uninfected peers. Research and practitioners have expressed...
Effects of test-and-treat versus preexposure prophylaxis on elimination of HIV transmission: Analysis of 24 HIV prevention trials
INTRODUCTION: In 2023, 28.8 million (72%) of 39.9 million people with HIV (PWH) worldwide were on treatment with viral suppression, while 11.1 million (28%) people had viraemia with the risk...
