Category Archives: Prevention, Engagement and Care Cascade

Structural and socio-cultural barriers to HIV prevention tools among key populations: A scoping review

2025

INTRODUCTION: Despite decades of HIV prevention efforts, key populations – MSM, transgender people, PWUD, sex workers, and migrants – remain disproportionately affected by HIV. Although prevention tools are widely available,...

Diagnostic accuracy of the WHO clinical staging system for detection of immunologically defined advanced HIV disease: A systematic review and meta-analysis

2025

Introduction People with advanced HIV disease (AHD) face high risks of severe illness and death. CD4 testing enables timely diagnosis and appropriate care, yet access remains limited in many settings....

Pharmacogenetics in tuberculosis-HIV coinfected populations: A systematic review of genetic variants influencing antiretroviral and anti-tuberculosis drug response

2025

Pharmacogenetics is a concept designed to tailor medication based on genetic profile to improve efficacy and reduce adverse effects. This personalized strategy shows considerable potential for populations facing complicated therapeutic...

Strategies for implementing HIV self-testing in diverse populations: An integrative review

2025

OBJECTIVES: to identify strategies for implementing HIV self-testing in populations. METHODS: an integrative review of MEDLINE/PubMed, Scopus, CINAHL, Web of Science, and LILACS databases. Full articles available online, in Portuguese,...

Prevalence of current substance and hazardous alcohol use among people with HIV and tuberculosis disease and its impact on tuberculosis treatment outcomes: A systematic review

2025

Objective: To examine the prevalence of current substance and hazardous alcohol use in people with HIV and tuberculosis (TB) disease and its impact on TB treatment outcomes. Methods: A systematic review following...

Assessment tools for evaluating nursing students’ knowledge on HIV prophylaxis: A scoping review

2025

AIM: To map instruments assessing nursing students’ knowledge of HIV prophylaxis and critically appraise their measurement properties using the COSMIN framework. DESIGN: Scoping review. METHODS: This scoping review was conducted...

Characterising concerns and misinformation shaping global HIV vaccine confidence and demand: A structured literature search and content analysis

2026

BACKGROUND: Demand for a future HIV vaccine, similar to other vaccines, is vulnerable to misinformation. A number of studies have examined HIV vaccine acceptability and demand, but few have systematically...

HIV pre-exposure prophylaxis among people with criminal justice involvement in the United States: A systematic review

2025

People with criminal justice involvement (PCJI) face a heightened risk of HIV yet remain underserved by prevention strategies such as pre-exposure prophylaxis (PrEP). This systematic review synthesizes current evidence on...

The reasons of late diagnosis in patients with HIV/AIDS: A meta-synthesis

2025

PURPOSE: To comprehensively integrate qualitative findings on the reasons of late diagnosis in HIV/AIDS patients and to encourage timely clinic consultations for advisory purposes. METHODS: A qualitative systematic review utilizing...

Human milk oligosaccharides, microbiome, antiretroviral therapy and HIV infected mothers: Reasons to still promote breastfeeding in HIV context of lactating countries, a mini-narrative review

2025

Breastfeeding is the preferred feeding for newborns during the first 6 months of life and until the age of 2 years or beyond. The benefits of breastfeeding remain significant, even in cases...

Integrating PrEP and sexual reproductive health services for adolescent girls and young women in South Africa: A scoping review

2025

Adolescent girls and young women (AGYW) in South Africa bear a disproportionate burden of the global HIV epidemic. Integrating PrEP into sexual and reproductive health (SRH) services offers a promising...

The association between different levels of suppressed viral load and the risk of sexual transmission of HIV among serodiscordant couples on antiretroviral therapy: A systematic review

2025

The risk of sexual transmission of HIV in serodiscordant couples when the partner living with HIV (PLHIV) uses antiretroviral therapy (ART) and maintains a suppressed viral load (VL) (< 200...

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