Category Archives: Prevention, Engagement and Care Cascade
Comparing clinical outcomes of antibiotics for treating Mycobacterium avium complex infection in adults with HIV: A systematic review and network meta-analysis
Background: This study aims to identify the comparative effects of different drug regimens in treating Mycobacterium avium complex (MAC). Methods: PubMed, EMBASE, CENTRAL, and EBSCO Open Dissertations were searched in September 2023....
Preferences for long-acting antiretroviral therapy among people with HIV: A systematic review of discrete choice experiments
BACKGROUND: Long-acting antiretroviral therapy (LA-ART) is emerging as a promising strategy to enhance treatment satisfaction and improve the quality of life for people living with HIV (PLWH). A comprehensive understanding...
Interventions to reduce HIV-related stigma among older people living with HIV in sub-Saharan Africa: A scoping review
HIV-related stigma remains a major barrier to testing, treatment, and quality of life, especially for the growing population of older people living with HIV (OPLWH, aged 50+). Such stigma intersects...
PrEP delivery for US adolescents and young adults: A systematic review and narrative synthesis
Despite proven efficacy in preventing human immunodeficiency virus (HIV) transmission, pre-exposure prophylaxis (PrEP) remains underutilized among adolescents and young adults (AYA) in the United States (US). This systematic review and...
Structural and socio-cultural barriers to HIV prevention tools among key populations: A scoping review
INTRODUCTION: Despite decades of HIV prevention efforts, key populations – MSM, transgender people, PWUD, sex workers, and migrants – remain disproportionately affected by HIV. Although prevention tools are widely available,...
Diagnostic accuracy of the WHO clinical staging system for detection of immunologically defined advanced HIV disease: A systematic review and meta-analysis
Introduction People with advanced HIV disease (AHD) face high risks of severe illness and death. CD4 testing enables timely diagnosis and appropriate care, yet access remains limited in many settings....
Barriers to and enablers of adherence to the treatment of active drug-sensitive tuberculosis in people living with HIV: A mixed method systematic review
BACKGROUND: Adherence to tuberculosis (TB) treatment is essential in improving treatment outcomes and reducing TB-related mortality. People living with HIV (PLWH) are at a higher risk of developing and dying...
Incidence of loss to follow-up among East African adults on antiretroviral therapy: A systematic review and meta-analysis
Background Individuals with human immunodeficiency virus receive antiretroviral treatment regardless of their clinical stage or CD4 count. While the “Universal Test and Treat” approach offers benefits, loss to follow-up remains...
An integrative review of PrEP promotion strategies at historically Black colleges and universities to reduce HIV disparities
PURPOSE OF REVIEW: We searched PubMed, CINAHL Plus, Embase, Scopus, Web of Science, and ERIC to identify peer-reviewed studies published between 2015 and 2025 that discussed PrEP at HBCUs. We...
Pre-exposure prophylaxis care engagement among men who have sex with men in the United States during the COVID-19 pandemic: A scoping review
The COVID-19 pandemic substantially impacted the pre-exposure prophylaxis (PrEP) care continuum among men who have sex with men (MSM). While PrEP use during the pandemic has been studied, regional differences...
Integration models for delivering COVID-19 vaccines through HIV services in low-and middle-income countries: A scoping review
BACKGROUND: The Coronavirus Disease 2019 (COVID-19) remains a major global public health issue. People living with HIV (PLHIV) are among the vulnerable groups facing a higher risk of severe outcomes....
