Category Archives: Prevention, Engagement and Care Cascade
Barriers and facilitators to oral HIV pre-exposure prophylaxis use in Australia: A scoping review comparing findings to Canada, New Zealand, and the United Kingdom
Oral HIV pre-exposure prophylaxis (PrEP) is highly effective, yet various barriers limit its potential as a HIV prevention strategy. This scoping review aimed to identify and quantify determinants of oral...
Perinatal outcomes associated with antiretroviral therapy for pregnant women living with HIV: An umbrella review
Background:Â The World Health Organization recommends antiretroviral therapy (ART) for pregnant women living with HIV (WLHIV), the vast majority of whom reside in sub-Saharan Africa. In recent years, many systematic reviews,...
Effectiveness of digital interventions in reducing chemsex-related health risks among mem who have sex with men (MSM): A systematic review
Chemsex among men who have sex with men (MSM) has emerged as a significant public health concern, creating an urgent need for effective harm-reduction strategies. Digital platforms are becoming a...
Implementation of therapeutic adherence in adult patients diagnosed with the human immunodeficiency virus: A systematic review
OBJECTIVES: To systematically map and summarize the available knowledge on interventions that promote medication adherence among adult HIV patients and to describe the current state of the art regarding the...
Indirect treatment comparison of the efficacy of long-acting injectable cabotegravir compared with lenacapavir for HIV pre-exposure prophylaxis
INTRODUCTION: Long-acting injectable cabotegravir (hereafter referred to as cabotegravir) is the first long-acting injectable approved for pre-exposure prophylaxis (PrEP) based on the HPTN 083 and 084 trials. Long-acting injectable lenacapavir...
The gut-immune axis in treated HIV infection: From mucosal damage to chronic inflammation and therapeutic opportunities—A clinician-oriented narrative review
Combined antiretroviral therapy (cART) has transformed HIV into a manageable chronic disease. However, people living with HIV (PLWH) experience a 16-year reduction in comorbidity-free life expectancy compared to HIV-negative individuals,...
Maternal, fetal, and neonatal outcomes of additional dihydroartemisinin-piperaquine to trimethoprim-sulfamethoxazole in intermittent preventive treatment for malaria in HIV-positive pregnancies: A systematic review and meta-analysis
PURPOSE: This systematic review evaluates the addition of Dihydroartemisinin-Piperaquine (DHA-PPQ) to Trimethoprim-Sulfamethoxazole (TMP-SMX) for Intermittent Preventive Treatment (IPT) in HIV-positive pregnancies, focusing on its effects on malaria infection, maternal adverse...
Effects of targeted interventions on HIV testing, knowledge and sexual risk behaviours among long-distance truck drivers: A systematic review and meta-analysis
Objectives We aimed to systematically summarise and quantify the empirical evidence on targeted interventions and their effects on various HIV prevention outcomes for long-distance truck drivers (LDTDs) globally. Design A...
Integrated service delivery models for triple elimination of mother to child transmission of human immunodeficiency virus, syphilis, and hepatitis B virus: A global systematic review and meta-analysis
BACKGROUND AND OBJECTIVES: Despite global commitment to the World Health Organization triple elimination initiative, evidence on integrated antenatal service delivery models that simultaneously address human immunodeficiency virus (HIV), syphilis, and...
Perspective of people living with HIV and healthcare workers on the uptake, barriers, and benefits of multimonth dispensing: A qualitative systematic review
INTRODUCTION: Multimonth dispensing (MMD) is a strategy in the HIV care continuum for people living with HIV (PLWH), especially for those who are virally suppressed. With the increase in MMD...
Simulation modeling for the design and evaluation of HIV drug resistance interventions: A systematic review of literature
Background The utility of antiretroviral therapy (ART) in the management of human immunodeficiency virus (HIV) is being challenged by growing HIV drug resistance (HIVDR). Although simulation modelling is useful for...
Integration of HIV, Hepatitis B, and C, and sexually transmitted infections services: A scoping review of the benefits and challenges
BACKGROUND: Integrating clinical programs and services is a cost-effective approach that can improve health and system outcomes. This review aimed to provide an overview of the benefits and challenges of...
