Category Archives: Prevention, Engagement and Care Cascade

Body fat changes in people living with HIV on antiretroviral therapy

2016

Although more than one in two HIV-infected persons may develop central fat accumulation soon after commencing antiretroviral therapy, the association between antiretroviral therapy and body fat changes has not been...

Safety of intrauterine devices among women with HIV: A systematic review

2016

BACKGROUND: Use of highly effective contraception among women living with HIV is critical to prevent unintended pregnancy and subsequent risk of maternal complications and perinatal HIV transmission. However, it is...

Work environments and HIV prevention: A qualitative review and meta-synthesis of sex worker narratives

2016

BACKGROUND: Sex workers (SWs) experience a disproportionately high burden of HIV, with evidence indicating that complex and dynamic factors within work environments play a critical role in mitigating or producing...

The effectiveness of mobile phone text messaging in improving medication adherence for patients with chronic diseases: A systematic review

2016

CONTEXT: Medication non-adherence is a commonly observed problem in the self-administration of treatment, regardless of the disease type. Text messaging reminders, as electronic reminders, provide an opportunity to improve medication...

Impact of opioid substitution therapy on antiretroviral therapy outcomes: A systematic review and meta-analysis

2016

BACKGROUND: Human immunodeficiency virus (HIV)-infected people who inject drugs (PWID) frequently encounter barriers accessing and remaining on antiretroviral therapy (ART). Some studies have suggested that opioid substitution therapy (OST) could...

Interventions targeting sexual and reproductive health and rights outcomes of young people living with HIV: A comprehensive review of current interventions from sub-Saharan Africa

2015

BACKGROUND: A growing number of young people (ages 10-24) are living with HIV (YPLWH) in sub-Saharan Africa (SSA). These YPLWH have particular needs and challenges related to their sexual and...

Transgender women, hormonal therapy and HIV treatment: A comprehensive review of the literature and recommendations for best practices

2016

INTRODUCTION: Studies have shown that transgender women (TGW) are disproportionately affected by HIV, with an estimated HIV prevalence of 19.1% among TGW worldwide. After receiving a diagnosis, HIV-positive TGW have...

Healthcare programmes for truck drivers in Sub-Saharan Africa: A systematic review and meta-analysis

2016

BACKGROUND: Truck drivers have unique health needs, and by virtue of their continuous travel, experience difficulty in accessing healthcare. Currently, planning for effective care is hindered by lack of knowledge...

Mobile health applications for HIV prevention and care in Africa

2016

PURPOSE OF REVIEW: More people have mobile phones in Africa than at any point in history. Mobile health (m-health), the use of mobile phones to support the delivery of health...

Systematic review to determine the prevalence of transmitted drug resistance mutations to rilpivirine in HIV-infected treatment-naive persons

2016

BACKGROUND: Transmitted drug resistance to antiretrovirals in HIV-1 infected individuals is rising in some regions, and could compromise the effectiveness of first-line treatment. It is important to understand the prevalence...

Pharmacologic prevention of human immunodeficiency virus in women: Practical approaches for the obstetrician and gynecologist

2015

IMPORTANCE: Obstetricians and gynecologists (Ob-Gyns) play a crucial role in efforts to detect and prevent human immunodeficiency virus (HIV) infection in women. Multiple strategies can be implemented into general practice...

Characteristics of men who have sex with men who use smartphone geosocial networking applications and implications for HIV interventions: A systematic review and meta-analysis

2016

Men who have sex with men (MSM) are increasingly using geosocial networking (GSN) mobile applications (apps) designed for MSM to socialize and seek sex partners. We systematically reviewed studies on...

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