Category Archives: Prevention, Engagement and Care Cascade

Option B+ for the prevention of mother-to-child transmission of HIV infection in developing countries: A review of published cost-effectiveness analyses

2016

OBJECTIVE: To review the published literature on the cost effectiveness of Option B+ (lifelong antiretroviral therapy) for preventing mother-to-child transmission (PMTCT) of HIV during pregnancy and breastfeeding to inform decision...

Comparisons of adherence to antiretroviral therapy in a high-risk population in China: A systematic review and meta-analysis

2016

BACKGROUND: Reports on antiretroviral therapy (ART) adherence are scare in China; we performed this meta-analysis to estimate ART adherence rates in different populations at high risk for HIV transmission in...

Health-information needs of HIV-positive adults in Latin America and the Caribbean: An integrative review of the literature

2016

An assessment of information needs is essential for care planning for patients living with chronic diseases such as human immunodeficiency virus (HIV). The extent to which these assessments have been...

Incidence of opportunistic infections and the impact of antiretroviral therapy among HIV-infected adults in low- and middle-income countries: A systematic review and meta-analysis

2016

BACKGROUND: To understand regional burdens and inform delivery of health services, we conducted a systematic review and meta-analysis to evaluate the effect of antiretroviral therapy (ART) on incidence of key...

Do behavioral scientists really understand HIV-related sexual risk behavior? A systematic review of longitudinal and experimental studies predicting sexual behavior

2015

Behavioral interventions to reduce sexual risk behavior depend on strong health behavior theory. By identifying the psychosocial variables that lead causally to sexual risk, theories provide interventionists with a guide...

Non-nucleoside reverse transcriptase inhibitor- versus ritonavir-boosted protease inhibitor-based regimens for initial treatment of HIV infection: A systematic review and meta-analysis of randomised trials

2016

BACKGROUND: Previous studies suggest that nonnucleoside reverse-transcriptase inhibitors (NNRTIs) cause faster virologic suppression, while ritonavir-boosted protease inhibitors (PI/r) recover more CD4 cells. However, individual trials have not been powered to...

Antiretroviral therapy among pregnant and postpartum women in China: A systematic review and meta-analysis

2016

BACKGROUND: The objectives of this study were to estimate the antiretroviral therapy (ART) rate and the proportion of women with adequate ART adherence (100%), and to identify the reasons for...

Assessing the role of masculinity in the transmission of HIV: A systematic review to inform HIV risk reduction counseling interventions for men who have sex with men

2015

HIV affects over 1.2 million people in the United States; a substantial number are men who have sex with men (MSM). Despite an abundance of literature evaluating numerous social/structural and...

Facilitators and barriers in HIV linkage to care interventions: A qualitative evidence review

2016

OBJECTIVE: To synthesize qualitative evidence on linkage to care interventions for people living with HIV. DESIGN: Systematic literature review. METHODS: We searched nineteen databases for studies reporting qualitative evidence on...

Generic antiretroviral drugs and HIV care: An economic review

2016

The cost of HIV care in European countries is high. Direct medical costs, in France, have been estimated at 500,000Euros per patient’s lifetime (20,000 Euros/year/patient). Overall, 73% of these costs...

A systematic review of HIV and STI behavior change interventions for female sex workers in the United States

2015

The lives of female sex workers (FSW) in the US are typically marked by substance abuse, violence, trauma, and poverty. These factors place FSW at risk for acquiring and transmitting...

Relationship-based predictors of sexual risk for HIV among MSM couples: A systematic review of the literature

2016

Behavioral and epidemiological studies report high risk for HIV among MSM couples. Over the last decade, studies have examined relationship dynamics associated with sexual risk for HIV. It is important...

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