Category Archives: Prevention, Engagement and Care Cascade

Effectiveness and safety of rilpivirine, a non-nucleoside reverse transcriptase inhibitor, in treatment-naive adults infected with HIV-1: A meta-analysis

2014

Objective: The aim of this study was to determine the effectiveness and safety of rilpivirine in treatment-naive adults infected with HIV-1. Methods: We ran duplicate searches of multiple databases and...

Disclosure of HIV serostatus among pregnant and postpartum women in sub-Saharan Africa: A systematic review

2015

Disclosure of one’s HIV status can help to improve uptake and retention in prevention of mother-to-child transmission of HIV services; yet, it remains a challenge for many women. This systematic...

HIV infection and cardiovascular disease

2014

AIMS: With the success of antiretroviral therapy (ART), non-human immunodeficiency virus (HIV)-related comorbidities like cardiovascular diseases (CVDs) are of increasing concern. We describe important recent research developments on the epidemiology...

Circumcision status and risk of HIV acquisition during heterosexual intercourse for both males and females: A meta-analysis

2015

In this study, we evaluated if male circumcision was associated with lower HIV acquisition for HIV (-) males and HIV (-) females during normal sexual behavior. We performed a systematic...

A systematic review of contemporary models of shared HIV care and HIV in primary care in high-income settings

2015

HIV shared care is uncommon in the UK although shared care could be a beneficial model of care. We review the literature on HIV shared care to determine current practice...

Predictors and correlates of adherence to combination antiretroviral therapy (ART) for chronic HIV infection: A meta-analysis

2014

BACKGROUND: Adherence to combination antiretroviral therapy (ART) is a key predictor of the success of human immunodeficiency virus (HIV) treatment, and is potentially amenable to intervention. Insight into predictors or...

HIV, antiretroviral therapy, and hypertensive disorders in pregnancy: A systematic review and meta-analysis

2015

BACKGROUND: There are data to suggest that infection with HIV or use of highly active antiretroviral therapy increases the risk of hypertensive disorders in pregnancy. This systematic review and meta-analysis...

Retention in care prior to antiretroviral treatment eligibility in sub-Saharan Africa: A systematic review of the literature

2015

OBJECTIVE: We aimed at summarising rates and factors associated with retention in HIV care prior to antiretroviral treatment (ART) eligibility in sub-Saharan Africa. DESIGN: We conducted a systematic literature review...

Systematic review and meta-analysis of community and facility-based HIV testing to address linkage to care gaps in sub-Saharan Africa

2015

HIV testing and counselling is the first crucial step for linkage to HIV treatment and prevention. However, despite high HIV burden in sub-Saharan Africa, testing coverage is low, particularly among...

Condom effectiveness in reducing heterosexual HIV transmission: A systematic review and meta-analysis of studies on HIV serodiscordant couples

2015

OBJECTIVE: This systematic review and meta-analysis aimed to reassess the effectiveness of condoms in reducing heterosexual transmission of HIV. METHODS: Medline, Scopus, and the ISI Web of Science databases were...

Safety and efficacy of lopinavir/ritonavir during pregnancy: A systematic review

2013

The co-formulated, ritonavir-boosted protease inhibitor lopinavir is a frequently used component of HAART for treatment of HIV-infected women during pregnancy and prevention of mother-to-child transmission. We performed a systematic review...

A meta-analysis investigating incidence and features of stroke in HIV-infected patients in the highly active antiretroviral therapy era

2015

OBJECTIVE: Recent studies have suggested a close biological and clinical association between HIV infection and risk of myocardial infarction, whereas contrasting data have been reported about incidence of stroke and...

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