Category Archives: Prevention, Engagement and Care Cascade
Option B+ for the prevention of mother-to-child transmission of HIV infection in developing countries: A review of published cost-effectiveness analyses
OBJECTIVE: To review the published literature on the cost effectiveness of Option B+ (lifelong antiretroviral therapy) for preventing mother-to-child transmission (PMTCT) of HIV during pregnancy and breastfeeding to inform decision...
Comparisons of adherence to antiretroviral therapy in a high-risk population in China: A systematic review and meta-analysis
BACKGROUND: Reports on antiretroviral therapy (ART) adherence are scare in China; we performed this meta-analysis to estimate ART adherence rates in different populations at high risk for HIV transmission in...
Health-information needs of HIV-positive adults in Latin America and the Caribbean: An integrative review of the literature
An assessment of information needs is essential for care planning for patients living with chronic diseases such as human immunodeficiency virus (HIV). The extent to which these assessments have been...
Incidence of opportunistic infections and the impact of antiretroviral therapy among HIV-infected adults in low- and middle-income countries: A systematic review and meta-analysis
BACKGROUND: To understand regional burdens and inform delivery of health services, we conducted a systematic review and meta-analysis to evaluate the effect of antiretroviral therapy (ART) on incidence of key...
Do behavioral scientists really understand HIV-related sexual risk behavior? A systematic review of longitudinal and experimental studies predicting sexual behavior
Behavioral interventions to reduce sexual risk behavior depend on strong health behavior theory. By identifying the psychosocial variables that lead causally to sexual risk, theories provide interventionists with a guide...
Non-nucleoside reverse transcriptase inhibitor- versus ritonavir-boosted protease inhibitor-based regimens for initial treatment of HIV infection: A systematic review and meta-analysis of randomised trials
BACKGROUND: Previous studies suggest that nonnucleoside reverse-transcriptase inhibitors (NNRTIs) cause faster virologic suppression, while ritonavir-boosted protease inhibitors (PI/r) recover more CD4 cells. However, individual trials have not been powered to...
Antiretroviral therapy among pregnant and postpartum women in China: A systematic review and meta-analysis
BACKGROUND: The objectives of this study were to estimate the antiretroviral therapy (ART) rate and the proportion of women with adequate ART adherence (100%), and to identify the reasons for...
Assessing the role of masculinity in the transmission of HIV: A systematic review to inform HIV risk reduction counseling interventions for men who have sex with men
HIV affects over 1.2 million people in the United States; a substantial number are men who have sex with men (MSM). Despite an abundance of literature evaluating numerous social/structural and...
Facilitators and barriers in HIV linkage to care interventions: A qualitative evidence review
OBJECTIVE: To synthesize qualitative evidence on linkage to care interventions for people living with HIV. DESIGN: Systematic literature review. METHODS: We searched nineteen databases for studies reporting qualitative evidence on...
Relationship-based predictors of sexual risk for HIV among MSM couples: A systematic review of the literature
Behavioral and epidemiological studies report high risk for HIV among MSM couples. Over the last decade, studies have examined relationship dynamics associated with sexual risk for HIV. It is important...
