Category Archives: Prevention, Engagement and Care Cascade
Pharmacologic prevention of human immunodeficiency virus in women: Practical approaches for the obstetrician and gynecologist
IMPORTANCE: Obstetricians and gynecologists (Ob-Gyns) play a crucial role in efforts to detect and prevent human immunodeficiency virus (HIV) infection in women. Multiple strategies can be implemented into general practice...
Characteristics of men who have sex with men who use smartphone geosocial networking applications and implications for HIV interventions: A systematic review and meta-analysis
Men who have sex with men (MSM) are increasingly using geosocial networking (GSN) mobile applications (apps) designed for MSM to socialize and seek sex partners. We systematically reviewed studies on...
The influence of neurocognitive impairment on HIV risk behaviors and intervention outcomes among high-risk substance users: A systematic review
Neurocognitive impairment (NCI) among high-risk substance users poses a substantial barrier to reducing risk behaviors in this population. Previous work suggests that NCI is intertwined in a close, reciprocal relationship...
HIV pre-exposure prophylaxis (PrEP): A review of current knowledge of oral systemic HIV PrEP in humans
PURPOSE: Despite established HIV prevention strategies and broadly available diagnostic strategies in developed western countries, rates of HIV new infections remain high. Alternative strategies for HIV prevention, particularly among men...
A systematic review of the effect of HIV infection and antiretroviral therapy on the risk of pre-eclampsia
BACKGROUND: The associations between HIV infection, antiretroviral therapy (ART), and pre-eclampsia are unclear. OBJECTIVES: To summarize research and clarify the implications of HIV and ART on pre-eclampsia risk. SEARCH STRATEGY:...
A systematic review of interventions to improve prevention of mother-to-child HIV transmission service delivery and promote retention
INTRODUCTION: The success of prevention of mother-to-child transmission of HIV (PMTCT) is dependent upon high retention of mother-infant pairs within these programmes. This is a systematic review to evaluate the...
Health system and community level interventions for improving antenatal care coverage and health outcomes
BACKGROUND: The World Health Organization (WHO) recommends at least four antenatal care (ANC) visits for all pregnant women. Almost half of pregnant women worldwide, and especially in developing countries do...
Association of opioid agonist therapy with the initiation of antiretroviral therapy — A systematic review
OBJECTIVES: People who inject drugs are at high risk of HIV infection but often face barriers in accessing medical care including access to antiretroviral therapy (ART). Evidence is available about...
Dual therapy treatment strategies for the management of patients infected with HIV: A systematic review of current evidence in ARV-naive or ARV-experienced, virologically suppressed patients
OBJECTIVE: We reviewed the current literature regarding antiretroviral (ARV)-sparing therapy strategies to determine whether these novel regimens can be considered appropriate alternatives to standard regimens for the initial treatment of...
Option B+ for the prevention of mother-to-child transmission of HIV infection in developing countries: A review of published cost-effectiveness analyses
OBJECTIVE: To review the published literature on the cost effectiveness of Option B+ (lifelong antiretroviral therapy) for preventing mother-to-child transmission (PMTCT) of HIV during pregnancy and breastfeeding to inform decision...
Comparisons of adherence to antiretroviral therapy in a high-risk population in China: A systematic review and meta-analysis
BACKGROUND: Reports on antiretroviral therapy (ART) adherence are scare in China; we performed this meta-analysis to estimate ART adherence rates in different populations at high risk for HIV transmission in...
