Category Archives: Prevention, Engagement and Care Cascade

Meta-analysis of studies comparing single and multi-tablet fixed dose combination HIV treatment regimens

2015

Availability of a single source review of once-daily fixed-dose single tablet regimen (STR) and multiple tablet fixed-dose regimen (MTR) would optimally inform healthcare providers and policy makers involved in the...

Evidence informing the intersection of HIV, aging and health: A scoping review

2014

The growing number of people over age 50 with HIV requires research, policy, and practice to develop a more comprehensive understanding of the health consequences of HIV in older individuals....

Beyond the bisexual bridge: Sexual health among U.S. men who have sex with men and women

2014

CONTEXT: Men who have sex with both men and women (MSMW) experience health problems in ways that distinguish them from men who only have sex with men (MSM) and men...

Cobicistat: A new opportunity in the treatment of HIV disease?

2014

INTRODUCTION: Cobicistat (Cobi), a selective novel CYP3A4 inhibitor, is an orally administered, non-antiretroviral pharmacokinetic enhancer which boosts the plasma levels of several drugs, including HIV-1 protease inhibitors and the integrase...

Self-transfer and mortality amongst adults lost to follow-up in ART programmes in low and middle-income countries: Systematic review and meta-analysis

2015

OBJECTIVE: To ascertain estimates of adult patients, recorded as lost to follow-up (LTFU) within antiretroviral treatment (ART) programmes, who have self-transferred care, died or truly stopped ART in low- and...

Mobile phone text messaging interventions for HIV and other chronic diseases: An overview of systematic reviews and framework for evidence transfer

2015

Background Strong international commitment and the widespread use of antiretroviral therapy have led to higher longevity for people living with human immune deficiency virus (HIV). Text messaging interventions have been...

New approaches to antiretroviral drug delivery: Challenges and opportunities associated with the use of long-acting injectable agents

2014

Research on improved treatment of HIV infection and pre-exposure prophylaxis continues. Poor adherence to treatment is the critical risk factor for virological failure and resistance development, and long-acting formulations of...

Systematic literature review and meta-analysis of renal function in human immunodeficiency virus (HIV)-infected patients treated with Atazanavir (ATV)-based regimens

2015

Some HIV antiretroviral therapies (ART) have been associated with renal toxicities, which become of increasing concern as HIV-infected patients age and develop comorbidities. The objective of this study was to...

CD4 enumeration technologies: A systematic review of test performance for determining eligibility for antiretroviral therapy

2015

BACKGROUND: Measurement of CD4+ T-lymphocytes (CD4) is a crucial parameter in the management of HIV patients, particularly in determining eligibility to initiate antiretroviral treatment (ART). A number of technologies exist...

The influence of religion on sexual HIV risk

2014

This systematic review examines the relationship between religion and sexual HIV risk behavior. It focuses primarily on how studies have conceptualized and defined religion, methodologies, and sexual risk outcomes. We...

Computer-based HIV adherence promotion interventions: A systematic review

2015

Researchers have instituted a range of methodologies to increase access to HIV adherence interventions. This article reviews studies published through January 2014 utilizing computer-based delivery of such interventions to persons...

Determinants of HIV outpatient service utilization: A systematic review

2015

Demands on HIV services are increasing as a consequence of the increased life-expectancy of HIV patients in the highly active antiretroviral therapy era. Understanding the factors that influence utilization of...

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