Category Archives: Prevention, Engagement and Care Cascade

Pre-exposure prophylaxis of HIV: A right way to go or a long way to go?

2016

Antiretroviral drugs are being tried as candidates for the pre-exposure prophylaxis (PrEP) against HIV for a considerable period, due to their potential for immediate inhibition of viral replication. Discrepancies in...

HIV behavioural interventions targeted towards older adults: A systematic review

2014

BACKGROUND: The increasing number of people living with HIV aged 50 years and older has been recognised around the world yet non-pharmacologic HIV behavioural and cognitive interventions specifically targeted to...

Sexual risk reduction interventions for HIV prevention among South African youth: A meta-analytic review

2013

OBJECTIVES: To examine the efficacy of sexual risk reduction interventions among South African youth. METHODS: Electronic databases were searched to identify studies published between 2007 and early 2013. Studies were...

Systemic immune activation in HIV and potential therapeutic options

2014

CONTEXT: Advancement in HIV treatment has evolved over the last two decades with the discovery of new drugs and approaches. Studies have demonstrated that HIV-infected individuals have elevated immune activation...

Global burden of transmitted HIV drug resistance and HIV-exposure categories: A systematic review and meta-analysis

2014

OBJECTIVES: Our aim was to review the global disparities of transmitted HIV drug resistance (TDR) in antiretroviral-naive MSM, people who inject drugs (PWID) and heterosexual populations in both high-income and...

The risk of non-melanoma skin cancer in HIV-infected patients: New data and meta-analysis

2015

BACKGROUND: The role of HIV/AIDS in non-melanoma skin cancer is not well defined. OBJECTIVES: We sought to update the evidence of the association between HIV/AIDS and risk of non-melanoma skin...

Service delivery interventions to improve adolescents’ linkage, retention and adherence to antiretroviral therapy and HIV care

2015

OBJECTIVES: Adolescents living with HIV face substantial difficulties in accessing HIV care services and have worse treatment outcomes than other age groups. The objective of this review was to evaluate...

The impact of water, sanitation, and hygiene interventions on the health and well-being of people living with HIV: A systematic review

2015

BACKGROUND: Access to improved water supply and sanitation is poor in low-income and middle-income countries. Persons living with HIV/AIDS (PLHIV) experience more severe diarrhea, hospitalizations, and deaths from diarrhea because...

Comparison of a user-centered design, self-management app to existing mHealth apps for persons living with HIV

2015

BACKGROUND: There is preliminary evidence that mobile health (mHealth) apps are feasible, attractive, and an effective platform for the creation of self-management tools for persons living with HIV (PLWH). As...

Eliminating mother-to-child transmission of the human immunodeficiency virus in sub-Saharan Africa: The journey so far and what remains to be done

2015

This review was carried out to provide a comprehensive overview of efforts toward elimination of mother-to-child transmission (MTCT) of human immunodeficiency virus (HIV) with respect to progress, challenges, and recommendations...

Systematic assessment of condom use measurement in evaluation of HIV prevention interventions: Need for standardization of measures

2014

When evaluating HIV prevention interventions, condom use is a common outcome measure used to assess changes in HIV-related behaviors; however, no widely accepted standards exist for its measurement. Using systematic...

Risk factors of HIV and other sexually transmitted infections in China: A systematic review of reviews

2015

BACKGROUND: Sexually Transmitted Infections (STIs) are a global challenge. China, once said to have eradicated STIs, is now facing a rapid rise in the prevalence of HIV/STIs. This review of...

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