Category Archives: Prevention, Engagement and Care Cascade

Equity in utilization of antiretroviral therapy for HIV-infected people in South Africa: A systematic review

2014

INTRODUCTION: About half a million people in South Africa are deprived of antiretroviral therapy (ART), and there is little systematic knowledge on who they are – e.g. by severity of...

eHealth interventions for HIV prevention in high-risk men who have sex with men: A systematic review

2014

BACKGROUND: While the human immunodeficiency virus (HIV) incidence rate has remained steady in most groups, the overall incidence of HIV among men who have sex with men (MSM) has been...

Systemic preexposure prophylaxis for HIV: Translating clinical data to clinical practice

2014

OBJECTIVE: To assess the real-world implications of oral tenofovir-emtricitabine (TDF-FTC) for HIV preexposure prophylaxis (PrEP) in clinical practice and highlight important considerations for its implementation. DATA SOURCES: A search of...

Revitalizing the HIV response in Pakistan: A systematic review and policy implications

2014

BACKGROUND: We sought to describe the epidemiology of HIV in Pakistan and prioritize interventions to improve the effectiveness and efficiency of the response to HIV. METHODS: We conducted a systematic...

Adherence to HIV postexposure prophylaxis: A systematic review and meta-analysis

2014

INTRODUCTION: We evaluated variations in completion rates for HIV postexposure prophylaxis (PEP) according to the exposure type (occupational, nonoccupational, and sexual assault), patient, and programme characteristics. METHODS: Four major databases...

HIV, HCV, and health-related harms among women who inject drugs: Implications for prevention and treatment

2015

BACKGROUND: Although an estimated 3.5 million women inject drugs globally, women are outnumbered 4 to one by men who inject drugs and are often ignored or overlooked in the development...

The changing role of HIV-associated oral candidiasis in the era of HAART

2015

Oral candidiasis is the most common fungal opportunistic infection to affect the oral cavity among HIV patients. The advent of highly active antiretroviral therapy (HAART) has changed the epidemiology of...

Integrating prevention interventions for people living with HIV into care and treatment programs: A systematic review of the evidence

2015

INTRODUCTION: This review assesses the impact of prevention interventions for people living with HIV on HIV-related mortality, morbidity, retention in care, quality of life, and prevention of ongoing HIV transmission...

Effects of integrated interventions on transmission risk and care continuum outcomes in persons living with HIV: Meta-analysis, 1996-2014

2015

BACKGROUND: Reducing HIV infection and improving outcomes along the continuum of HIV care are high priorities of the US National HIV/AIDS strategy. Interventions that target multiple problem behaviors simultaneously in...

Long-term virological outcomes of first-line antiretroviral therapy for HIV-1 in low- and middle-income countries: A systematic review and meta-analysis

2015

BACKGROUND: More than 11.7 million people are currently receiving antiretroviral therapy (ART) in low- and middle-income countries (LMICs), and focused efforts are needed to ensure high levels of adherence and...

Enhancing linkage and retention in HIV care: A review of interventions for highly resourced and resource-poor settings

2014

Given the widespread availability of effective antiretroviral therapy, engagement of HIV-infected persons in care is a global priority. We reviewed 51 studies, published in the past decade, assessing strategies for...

Are couple-based interventions more effective than interventions delivered to individuals in promoting HIV protective behaviors? A meta-analysis

2015

Despite several advantages to bringing couples together to learn how to protect themselves and new-born children from the risk of HIV infection, most interventions are designed for individuals or groups,...

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