Category Archives: Prevention, Engagement and Care Cascade

Eliminating mother-to-child transmission of the human immunodeficiency virus in sub-Saharan Africa: The journey so far and what remains to be done

2015

This review was carried out to provide a comprehensive overview of efforts toward elimination of mother-to-child transmission (MTCT) of human immunodeficiency virus (HIV) with respect to progress, challenges, and recommendations...

Enhancing linkage and retention in HIV care: A review of interventions for highly resourced and resource-poor settings

2014

Given the widespread availability of effective antiretroviral therapy, engagement of HIV-infected persons in care is a global priority. We reviewed 51 studies, published in the past decade, assessing strategies for...

Are couple-based interventions more effective than interventions delivered to individuals in promoting HIV protective behaviors? A meta-analysis

2015

Despite several advantages to bringing couples together to learn how to protect themselves and new-born children from the risk of HIV infection, most interventions are designed for individuals or groups,...

Is the sexual behaviour of young people in sub-Saharan Africa influenced by their peers? A systematic review

2015

Adolescents in sub-Saharan Africa are highly vulnerable to HIV, other sexually transmitted infections (STIs) and unintended pregnancies. Evidence for the effectiveness of individual behaviour change interventions in reducing incidence of...

Efficacy of inactivated hepatitis a vaccine in HIV-infected patients: A hierarchical Bayesian meta-analysis

2006

Patients with human immunodeficiency virus-1 (HIV) have elevated risk for hepatitis A virus (HAV) coinfection. Sequelae from coinfection include increased risk of liver-related morbidity and mortality. This study synthesizes the...

Equity in utilization of antiretroviral therapy for HIV-infected people in South Africa: A systematic review

2014

INTRODUCTION: About half a million people in South Africa are deprived of antiretroviral therapy (ART), and there is little systematic knowledge on who they are – e.g. by severity of...

eHealth interventions for HIV prevention in high-risk men who have sex with men: A systematic review

2014

BACKGROUND: While the human immunodeficiency virus (HIV) incidence rate has remained steady in most groups, the overall incidence of HIV among men who have sex with men (MSM) has been...

Systemic preexposure prophylaxis for HIV: Translating clinical data to clinical practice

2014

OBJECTIVE: To assess the real-world implications of oral tenofovir-emtricitabine (TDF-FTC) for HIV preexposure prophylaxis (PrEP) in clinical practice and highlight important considerations for its implementation. DATA SOURCES: A search of...

Revitalizing the HIV response in Pakistan: A systematic review and policy implications

2014

BACKGROUND: We sought to describe the epidemiology of HIV in Pakistan and prioritize interventions to improve the effectiveness and efficiency of the response to HIV. METHODS: We conducted a systematic...

Adherence to HIV postexposure prophylaxis: A systematic review and meta-analysis

2014

INTRODUCTION: We evaluated variations in completion rates for HIV postexposure prophylaxis (PEP) according to the exposure type (occupational, nonoccupational, and sexual assault), patient, and programme characteristics. METHODS: Four major databases...

HIV, HCV, and health-related harms among women who inject drugs: Implications for prevention and treatment

2015

BACKGROUND: Although an estimated 3.5 million women inject drugs globally, women are outnumbered 4 to one by men who inject drugs and are often ignored or overlooked in the development...

The changing role of HIV-associated oral candidiasis in the era of HAART

2015

Oral candidiasis is the most common fungal opportunistic infection to affect the oral cavity among HIV patients. The advent of highly active antiretroviral therapy (HAART) has changed the epidemiology of...

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