Category Archives: Prevention, Engagement and Care Cascade

Meta-analysis of the effectiveness of HIV prevention interventions for women

2002

The present study is a meta-analysis of the effectiveness of HIV prevention interventions for women in the USA. Twenty-four articles from 1989-1997 were included. We evaluated five ethnic groupings (All...

Vaginal disinfection during labour for reducing the risk of mother-to-child transmission of HIV infection

2002

BACKGROUND: Mother-to-child transmission (MTCT) of HIV infection is one of the most tragic consequences of the HIV epidemic, especially in resource-limited countries, resulting in about 650 000 new paediatric HIV...

Clinical utility of biomarkers of endothelial activation and coagulation for prognosis in HIV infection: A systematic review

2013

INTRODUCTION: HIV infection is associated with vascular dysfunction and adverse cardiovascular outcomes. Our objective was to review the evidence regarding the clinical utility of endothelial activation and coagulation biomarkers for...

Megestrol acetate for the treatment of anorexia-cachexia syndrome

2005

BACKGROUND: Megestrol acetate (MA) is currently used to improve appetite and to increase weight in cancer-associated anorexia. In 1993 MA was approved by the USA’s Federal Drug Administration for the...

Substitution treatment of injecting opioid users for prevention of HIV infection

2008

BACKGROUND: Injecting drug users are vulnerable to infection with HIV and other blood borne viruses as a result of collective use of injecting equipment as well as sexual behaviour. OBJECTIVES:...

Mobility and HIV in Central America and Mexico: A critical review

2012

Mobility is a key determinant of HIV/sexually transmitted infection (STI) transmission dynamics in Asia and Africa. Scant data exist regarding its dynamic impacts on HIV/STI risk in Central America and...

Considerations for implementing oral preexposure prophylaxis: A literature review

2014

Oral preexposure prophylaxis (PrEP) is in its infancy as an approved biomedical intervention; therefore, research is needed to understand the issues surrounding its implementation. The purpose of this literature review...

Barriers to participating in an HIV vaccine trial: A systematic review

2004

The enrolling of adequate participants into HIV experimental drug trials presents an important challenge. We systematically reviewed the literature to identify barriers and concerns amongst HIV patients to participation in...

Efficacy and safety of cesarean delivery for prevention of mother-to-child transmission of HIV-1

2005

BACKGROUND: Cesarean section before labor and before ruptured membranes (“elective cesarean section”, or ECS) has been introduced as an intervention for the prevention of mother-to-child transmission (MTCT) of HIV-1. The...

Unstructured treatment interruption of antiretroviral therapy in clinical practice: A systematic review

2011

Objective To characterize the frequency, reasons, risk factors, and consequences of unstructured anti-retroviral treatment interruptions. Method Systematic review. Results Seventy studies were included. The median proportion of patients interrupting treatment...

Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection

2005

BACKGROUND: Mother-to-child transmission (MTCT) of HIV is the dominant mode of acquisition of HIV infection for children, currently resulting in more than 2000 new paediatric HIV infections each day worldwide....

Cotrimoxazole for prophylaxis or treatment of opportunistic infections of HIV/AIDS in patients with previous history of hypersensitivity to cotrimoxazole

2007

BACKGROUND: Opportunistic infections continue to cause a significant amount of morbidity and mortality worldwide in patients infected with HIV. Trimethoprim-sulfamethoxazole (cotrimoxazole) is used in the treatment and prophylaxis of several...

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