Category Archives: Prevention, Engagement and Care Cascade

Treatment for leiomyosarcoma and leiomyoma in children with HIV infection

2010

BACKGROUND: Smooth muscle tumour (SMT) composed of leiomyoma and leiomyosarcoma recently has been described in many HIV-infected children. Leiomyosarcoma has become the second most frequent malignancy in children with HIV...

Abstinence-plus programs for HIV infection prevention in high-income countries

2008

BACKGROUND: Abstinence-plus interventions promote sexual abstinence as the best means of preventing acquisition of HIV, but also encourage safer-sex strategies (eg condom use) for sexually active participants. OBJECTIVES: To assess...

Progressive resistive exercise interventions for adults living with HIV/AIDS

2007

BACKGROUND: Due to medical advancements, many people living with HIV infection in developed countries are living longer (Palella 1998). HIV infection can now present as a chronic illness with an...

Behavioral interventions to promote condom use among women living with HIV

2011

BACKGROUND: High rates of HIV infection among women of reproductive age have dramatic consequences for personal and public health. Prophylaxis during sexual intercourse in the form of condoms has been...

Best-evidence interventions: Findings from a systematic review of HIV behavioral interventions for US populations at high risk, 2000-2004

2007

OBJECTIVES: The Centers for Disease Control and Prevention’s HIV/AIDS Prevention Research Synthesis Team conducted a systematic review of US-based HIV behavioral intervention research literature from 2000 through 2004 to identify...

A meta-analysis of adherence to antiretroviral therapy and virologic responses in HIV-infected children, adolescents, and young adults

2013

The relationship between adherence to antiretroviral therapy (ART) and virologic outcomes in HIV+ children, adolescents, and young adults has been notably understudied, with much of the extant research focused on...

Probiotics: Potential to prevent HIV and sexually transmitted infections in women

2008

Women are at significant risk of human immunodeficiency virus (HIV) and sexually transmitted infection (STI) acquisition with the genital mucosa serving as the main portal of infection. Exogenously supplied lactobacillus...

Efficacy of antiretroviral drugs in reducing mother-to-child transmission of HIV in Africa: A meta-analysis of published clinical trials

2008

Antiretroviral drugs (ARVs) have been shown to be efficacious in decreasing mother-to-child transmission (MTCT) of HIV. A summary estimate of the efficacy of ARVs in reducing MTCT is important for...

Cotrimoxazole prophylaxis for opportunistic infections in children with HIV infection

2003

Background: The majority of children with HIV infection live in low-income countries without access to antiretroviral drugs. The prevention and early treatment of opportunistic infections are the mainstay of their...

The unique features of pediatric HIV-1 in sub-Saharan Africa

2008

In order to adapt African programs for antiretroviral treatment (ART) to children’s needs, a good understanding of the unique features of pediatric HIV in Africa and realistic expectations of the...

School-based teenage pregnancy prevention programs: A systematic review of randomized controlled trials

2005

We compared school-based abstinence-only programs with those including contraceptive information (abstinence-plus) to determine which has the greatest impact on teen pregnancy. The United States has one of the highest rates...

Effects of nucleoside reverse transcriptase inhibitor backbone on the efficacy of first-line boosted highly active antiretroviral therapy based on protease inhibitors: Meta-regression analysis of 12 clinical trials in 5168 patients

2009

Objectives: Tenofovir/emtricitabine (TDF/FTC) and abacavir/lamivudine (ABC/3TC) are widely used with ritonavir (RTV)-boosted protease inhibitors (PIs) as first-line highly active antiretroviral therapy (HAART), but there is conflicting evidence on their relative...

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