Category Archives: Prevention, Engagement and Care Cascade
Stigma in the HIV/AIDS epidemic: A review of the literature and recommendations for the way forward
Although stigma is considered a major barrier to effective responses to the HIV/AIDS epidemic, stigma reduction efforts are relegated to the bottom of AIDS programme priorities. The complexity of HIV/AIDS-related...
Antiviral treatment for chronic hepatitis C in patients with human immunodeficiency virus
BACKGROUND: Antiviral treatment for chronic hepatitis C may be less effective if patients are co-infected with human immunodeficiency virus (HIV). OBJECTIVES: To assess the benefits and harms of antiviral treatment...
HIV-1 and intestinal helminth review update: Updating a Cochrane Review and building the case for treatment and has the time come to test and treat?
Intestinal helminth infection activates and dysregulates the immune system and impacts the host’s capacity to respond to illness. Such neglected tropical infections exact the greatest burden on resource-limited settings and...
A systematic review to quantitatively evaluate ‘Stepping Stones’: A participatory community-based HIV/AIDS prevention intervention
This first independent systematic review examined evidence for the effectiveness of the stepping stones intervention in HIV prevention. To reduce HIV transmission it addresses gender roles and promotes equitable relationships....
Effectiveness of pediatric antiretroviral therapy in resource-limited settings: A systematic review and meta-analysis
BACKGROUND: Responses to antiretroviral therapy (ART) among human immunodeficiency virus (HIV)-infected children in resource-limited settings have recently been reported, but outcomes vary. We sought to derive pooled estimates of the...
Sexual health education interventions for young people: A methodological review
Objectives: To locate reports of sexual health education interventions for young people, assess the methodological quality of evaluations, identify the subgroup with a methodologically sound design, and assess the evidence...
The epidemiology of human immunodeficiency virus infection, sexually transmitted infections, and associated risk behaviors among men who have sex with men in the Mekong Subregion and China: implications for policy and programming
BACKGROUND: Little systematic knowledge is available regarding risk behaviors and the prevalence of human immunodeficiency virus (HIV) and sexually transmitted infections (STI) in populations of men having sex with men...
Does highly active antiretroviral therapy improve neurocognitive function? A systematic review
Highly active antiretroviral therapy (HAART) reduces the incidence of human immunodeficiency virus (HIV) dementia (HAD), whereas the overall prevalence appears to have increased. Recent changes to diagnostic nosology have emphasized...
