Category Archives: Prevention, Engagement and Care Cascade

Responding to her question: A review of the influence of pregnancy on HIV disease progression in the context of expanded access to HAART in sub-Saharan Africa

2009

In 2007, sub-Saharan Africa was home to over half of all women living with HIV. The vast majority of these women are of reproductive age, which raises concerns about the...

Male circumcision for the prevention of heterosexually acquired HIV infection: A meta-analysis of randomized trials involving 11,050 men

2008

OBJECTIVES: Observational studies and a small collection of randomized controlled trials (RCTs) suggest that male circumcision may significantly reduce HIV transmission between sero-discordant contacts. The Joint United Nations Programme on...

Topical microbicides for prevention of sexually transmitted infections

2012

BACKGROUND: Two decades of research on topical microbicides for prevention of sexually transmitted infections (STIs) have had limited success. However, new microbicide randomised controlled trial (RCT) data have recently been...

The Indian pediatric HIV epidemic: A systematic review

2008

Despite an estimated 70,000 Indian children living with HIV infection, little is known about India’s pediatric HIV epidemic. Generalizations about epidemiology, natural history, and treatment outcomes from other resource-limited settings...

Systematic review and meta-analysis: Influence of smoking cessation on incidence of pneumonia in HIV

2013

BACKGROUND: Smoking is common in people infected with HIV but cessation support is not a routine part of clinical care. The aim was to assess whether smoking is a risk...

What is the relevance of mental health to HIV/AIDS care and treatment programs in developing countries? A systematic review

2006

The expansion of AIDS treatment initiatives in resource-poor settings provides an opportunity for integrating mental health care into these programs. This systematic review of the literature on HIV and mental...

A systematic review of probiotics as a potential intervention to restore gut health in HIV infection

2013

Probiotics have beneficial effects on the gut in numerous conditions. The purpose of this paper is to present a review of the current literature on probiotics used in chronic illnesses...

High mortality amongst adolescents and adults with bacterial meningitis in sub-Saharan Africa: An analysis of 715 cases from Malawi

2013

Mortality from bacterial meningitis in African adults is significantly higher than those in better resourced settings and adjunctive therapeutic interventions such as dexamethasone and glycerol have been shown to be...

HIV voluntary counseling and testing and behavioral risk reduction in developing countries: A meta-analysis, 1990-2005.

2008

The effectiveness of HIV voluntary counseling and testing (VCT) in reducing HIV risk behaviors in developing countries was assessed using meta-analytic methods. A standardized protocol was used for searching, acquiring,...

The Impact of DSM-IV Mental Disorders on Adherence to Combination Antiretroviral Therapy Among Adult Persons Living with HIV/AIDS: A Systematic Review

2012

This is a systematic review of eighty-two published studies investigating the impact of DSM-IV mental disorders on combination antiretroviral therapy (cART) adherence and persistence among persons living with HIV/AIDS (PLWHA)....

Isoniazid prophylaxis for tuberculosis in HIV infection: A meta-analysis of randomized controlled trials

1999

OBJECTIVES: To evaluate the efficacy of isoniazid for the prevention of tuberculosis in tuberculin skin test-positive and negative individuals with HIV infection. DESIGN: Meta-analysis of randomized controlled trials. SETTING: Seven...

Response rates to pegylated interferon and ribavirin in HCV/HIV coinfection: A research synthesis

2007

Several recent trials have determined varying rates of response to pegylated interferon plus ribavirin (peg-IFN + RIB) in hepatitis C virus (HCV)/human immunodeficiency virus-coinfected patients. We sought to identify a...

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