Category Archives: Prevention, Engagement and Care Cascade

Role of genetic diversity amongst HIV-1 non-B subtypes in drug resistance: A systematic review of virologic and biochemical evidence

2008

The genetic diversity of HIV-1 has required its classification into types and subtypes. There is controversy as to how and to what extent genetic diversity may affect the emergence of...

Treatment of chronic hepatitis C in haemophilic patients with interferon and ribavirin: A meta-analysis

2008

BACKGROUND: Hepatitis C virus (HCV) infection is a major cause of morbidity and mortality among haemophilic patients who were treated with clotting factor concentrates before the availability of virus-inactivated factors...

A systematic review of behavioral interventions to prevent HIV infection and transmission among heterosexual, adult men in low-and middle-income countries

2013

Prevention of new HIV infections needs to move to the forefront in the fight against HIV and AIDS. In the current economic crisis, low- and middle-income countries (LMICs) should invest...

Motivational interviewing targeting risk reduction for people with HIV: A systematic review

2012

Due to the co-occurrence of sexual risk behaviors and substance use among HIV-positive individuals, there is often a need for HIV prevention efforts to target multiple behaviors. Motivational Interviewing (MI),...

Meta-analytical studies on the epidemiology, prevention, and treatment of human immunodeficiency virus infection

2009

Since the beginning of the epidemic, extensive research has been conducted in the field of HIV infection. Original research and subsequent meta-analyses have contributed to a better understanding of the...

HIV status in discordant couples in sub-Saharan Africa: A systematic review and meta-analysis

2010

BACKGROUND: Most couples affected by HIV/AIDS in sub-Saharan Africa live in discordant relationships. Men are thought to be the index case in most relationships, and most social marketing and awareness...

Suppression of HBV by tenofovir in HBV/HIV coinfected patients: A systematic review and meta-analysis.

2013

BACKGROUND: Hepatitis B coinfection is common in HIV-positive individuals and as antiretroviral therapy has made death due to AIDS less common, hepatitis has become increasingly important. Several drugs are available...

The evolving design and methods for trials evaluating the safety of candidate vaginal microbicides: A systematic review

2013

Vaginal preexposure prophylaxis is a promising biomedical tool for HIV prevention. Although guidelines for the clinical assessment of microbicides are available, validated markers for product safety are lacking. To inform...

Technology-based self-care methods of improving antiretroviral adherence: A systematic review

2011

BACKGROUND: As HIV infection has shifted to a chronic condition, self-care practices have emerged as an important topic for HIV-positive individuals in maintaining an optimal level of health. Self-care refers...

Epidemiology of HIV infection in the Middle East and North Africa

2010

OBJECTIVE: The Middle East and North Africa (MENA) region continues to be perceived as a region with very limited HIV epidemiological data, raising many controversies about the status of the...

Barriers of enrolment in HIV vaccine trials: A review of HIV vaccine preparedness studies

2011

Barriers to participation in an HIV vaccine trial have been examined in many HIV vaccine preparedness studies (VPS). These barriers can be understood in terms of the locus of the...

Does epoetin alfa improve health-related quality of life in chronically ill patients with anemia: Summary of trials of cancer, HIV/AIDS, and chronic kidney disease

2008

OBJECTIVES: Anemia, defined as having low levels of hemoglobin (HGB), is caused by disease-related (e.g., bone marrow suppression, nutritional deficiency) or treatment-related (e.g., chemotherapy, antiretroviral therapy) factors. Although epoetin alfa...

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