Category Archives: Prevention, Engagement and Care Cascade
A systematic review and meta-regression of temporal trends in adult CD4(+) cell count at presentation to HIV care, 1992-2011
Background. The clinical status of human immunodeficiency virus (HIV)-positive persons at the time of presentation to medical care has important individual- and population-level implications. Methods. We synthesized the literature on...
HIV prevention for South African youth: which interventions work? A systematic review of current evidence
BACKGROUND: In South Africa, HIV prevalence among youth aged 15-24 is among the world’s highest. Given the urgent need to identify effective HIV prevention approaches, this review assesses the evidence...
Nursing research and the prevention of infectious diseases among vulnerable populations
Racial and ethnic minorities, women and infants, youth, and other special needs populations have been found to be disproportionately affected by infectious disease morbidity and mortality, particularly Human Immunodeficiency Syndrome/Acquired...
Treatment outcomes of treatment-naive Hepatitis C patients co-infected with HIV: A systematic review and meta-analysis of observational cohorts
INTRODUCTION: Co-infection with Hepatitis C (HCV) and HIV is common and HIV accelerates hepatic disease progression due to HCV. However, access to HCV treatment is limited and success rates are...
Retention in care of HIV-infected children from HIV test to start of antiretroviral therapy: Systematic review
BACKGROUND: In adults it is well documented that there are substantial losses to the programme between HIV testing and start of antiretroviral therapy (ART). The magnitude and reasons for loss...
Alcohol and sexual risk reduction interventions among people living in Russia: A systematic review and meta-analysis
Russia has one of the highest rates of alcohol consumption and is experiencing one of the fastest-growing HIV epidemics in the world. Given these co-occurring health problems, we systematically reviewed...
Early mortality in adults initiating antiretroviral therapy (ART) in low- and middle-income countries (LMIC): A systematic review and meta-analysis
BACKGROUND: We systematically reviewed observational studies of early mortality post-antiretroviral therapy (ART) initiation in low- and middle-income countries (LMIC) in Asia, Africa, and Central and South America, as defined by...
HIV risk among men who have sex with men who have experienced childhood sexual abuse: Systematic review and meta-analysis
Previous research has indicated a high prevalence of childhood sexual abuse (CSA) among men who have sex with men (MSM) in the United States, and has suggested that CSA history...
Sex differences in HIV outcomes in the highly active antiretroviral therapy era: A systematic review.
Objective: To assess sex disparities in AIDS clinical and laboratory outcomes in the HAART era. Design: Systematic review of published literature on mortality, disease progression, and laboratory outcomes among persons...
Antihypertensive drugs in patients treated with antiretrovirals
OBJECTIVE: To review the literature for information regarding pharmacokinetic interactions between antiretrovirals and antihypertensive agents, evaluate the clinical significance of these interactions, and analyze the effect of antihypertensive drugs on...
