Category Archives: Prevention, Engagement and Care Cascade
Comparative efficacy of Lamivudine and emtricitabine: A systematic review and meta-analysis of randomized trials
INTRODUCTION: Lamivudine and emtricitabine are considered equivalent by several guidelines, but evidence of comparable efficacy is conflicting. METHODS: We searched two databases up to June 30 2013 to identify randomized...
Efficacy of peer-led interventions to reduce unprotected anal intercourse among men who have sex with men: A meta-analysis.
OBJECTIVE: To conduct a systematic review and meta-analysis to evaluate the efficacy of peer-led interventions in reducing unprotected anal intercourse (UAI) among men who have sex with men (MSM). METHODS:...
Livelihood security and adherence to antiretroviral therapy in low and middle income settings: A systematic review
INTRODUCTION: We sought to examine the association between livelihood security and adherence to antiretroviral therapy (ARVs) in low- and middle-income countries (LIMC). METHODS: Performing a systematic review, we searched, independently...
Impact of viral load and the duration of primary infection on HIV transmission: Systematic review and meta-analysis
OBJECTIVES: HIV ‘treatment as prevention’ (TasP) describes early treatment of HIV-infected patients intended to reduce viral load and transmission. Crucial assumptions for estimating TasP’s effectiveness are the underlying estimates of...
HIV, alcohol dependence, and the criminal justice system: A review and call for evidence-based treatment for released prisoners
BACKGROUND: People with both HIV and alcohol use disorders (AUDs) are disproportionately concentrated within the U.S. criminal justice system; approximately one-quarter of all people with HIV cycle through the system...
The validity of the modification of diet in renal disease formula in HIV-infected patients: A systematic review
RATIONALE, AIMS AND OBJECTIVES: Renal dysfunction is highly prevalent in HIV-infected patients and may require dose adjustment of renally excreted antiretroviral drugs. The Modification of Diet in Renal Disease (MDRD)-4...
Heterosexual risk of HIV infection in China: Systematic review and meta-analysis
BACKGROUND: Heterosexual sex has become the dominant transmission route in China. Recently studies reported high heterogeneity in heterosexual transmission risk in resource-limited countries. The aim of this study was to...
Integrating prevention of mother-to-child HIV transmission programs to improve uptake: A systematic review
Background: We performed a systematic review to assess the effect of integrated perinatal prevention of mother-to-child transmission of HIV interventions compared to non- or partially integrated services on the uptake...
Cost-effectiveness of community-level approaches to HIV prevention: A review
Effective community-level HIV prevention strategies have the potential to reach large numbers of at-risk individuals at relatively small per-capita costs, and therefore to be highly cost-effective. We review the published...
Nonoxynol-9 spermicide for prevention of vaginally acquired HIV and other sexually transmitted infections: Systematic review and meta-analysis of randomised controlled trials including more than 5000 women
We aimed to determine the effectiveness of the vaginally administered spermicide nonoxynol-9 (N-9) among women for the prevention of HIV and other sexually transmitted infections (STIs). We did a systematic...
