Category Archives: Prevention, Engagement and Care Cascade

Co-formulated abacavir-lamivudine-zidovudine for initial treatment of HIV infection and AIDS

2013

Background: UNAIDS estimates that 34 million people are currently living with the human immunodeficiency virus (HIV) worldwide. Currently recommended regimens for initiating HIV treatment consist of either a non-nucleoside reverse...

Syphilis in drug users in low and middle income countries

2010

BACKGROUND: Genital ulcer disease (GUD), including syphilis, is an important cause of morbidity in low and middle income (LMI) countries and syphilis transmission is associated with HIV transmission. METHODS: We...

Induction effects of ritonavir: Implications for drug interactions

2008

OBJECTIVE: To review the literature on the induction effects of ritonavir on the cytochrome P450 enzyme system and glucuronyl transferase and identify resultant established and potential drug interactions. DATA SOURCES:...

A review of clinical trials to prevent mother-to-child HIV-1 transmission in Africa and inform rational intervention strategies

2002

No abstract.

Immune reconstitution inflammatory syndrome associated with Mycobacterium tuberculosis infection: A systematic review

2010

HIV and tuberculosis (TB) are leading global causes of mortality and morbidity. Highly active antiretroviral therapy (HAART) is often initiated in patients being treated for TB. The immune recovery associated...

Sexual risk reduction interventions for patients attending sexually transmitted disease clinics in the United States: A meta-analytic review, 1986 to early 2009

2010

Sexually transmitted disease (STD) patients are more likely to experience a future STD including human immunodeficiency virus (HIV). The aim of this study was to examine the efficacy of behavioral...

Risk of cardiovascular disease from antiretroviral therapy for HIV: A systematic review

2013

BACKGROUND: Recent studies suggest certain antiretroviral therapy (ART) drugs are associated with increases in cardiovascular disease. PURPOSE: We performed a systematic review and meta-analysis to summarize the available evidence, with...

Rethinking the heterosexual infectivity of HIV-1: A systematic review and meta-analysis

2008

Studies of cumulative HIV incidence suggest that cofactors such as genital ulcer disease, HIV disease stage, and male circumcision influence HIV transmission; however, the heterosexual infectivity of HIV-1 is commonly...

Explaining racial disparities in HIV/AIDS incidence among women in the U.S.: A systematic review

2008

Surveillance data indicate that HIV incidence among Black women is more than 20 times that among White women and more than 4 times that among Hispanic women. Several studies have...

Use of electronic reminder devices to improve adherence to antiretroviral therapy: A systematic review

2008

Adherence to prescribed antiretroviral therapy (ART) is one of the strongest predictors of progression to AIDS and death among people living with HIV/AIDS. Incorrect or inconsistent adherence to ART compromises...

Liver transplant outcomes in HIV-infected patients: A systematic review and meta-analysis with synthetic cohort

2011

OBJECTIVES: : The relative success of liver transplantation in those with HIV compared to HIV-uninfected individuals remains a point of intense debate. We aimed to evaluate the effectiveness of liver...

Adverse events associated with nevirapine use in pregnancy: A systematic review and meta-analysis

2013

INTRODUCTION: The risk of adverse drug events associated with nevirapine (NVP) is suggested to be greater in pregnant women. We conducted a systematic review and meta-analysis of severe adverse events...

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