Category Archives: Prevention, Engagement and Care Cascade
Risk of cardiovascular disease from antiretroviral therapy for HIV: A systematic review
BACKGROUND: Recent studies suggest certain antiretroviral therapy (ART) drugs are associated with increases in cardiovascular disease. PURPOSE: We performed a systematic review and meta-analysis to summarize the available evidence, with...
Rethinking the heterosexual infectivity of HIV-1: A systematic review and meta-analysis
Studies of cumulative HIV incidence suggest that cofactors such as genital ulcer disease, HIV disease stage, and male circumcision influence HIV transmission; however, the heterosexual infectivity of HIV-1 is commonly...
Use of electronic reminder devices to improve adherence to antiretroviral therapy: A systematic review
Adherence to prescribed antiretroviral therapy (ART) is one of the strongest predictors of progression to AIDS and death among people living with HIV/AIDS. Incorrect or inconsistent adherence to ART compromises...
Liver transplant outcomes in HIV-infected patients: A systematic review and meta-analysis with synthetic cohort
OBJECTIVES: : The relative success of liver transplantation in those with HIV compared to HIV-uninfected individuals remains a point of intense debate. We aimed to evaluate the effectiveness of liver...
Adverse events associated with nevirapine use in pregnancy: A systematic review and meta-analysis
INTRODUCTION: The risk of adverse drug events associated with nevirapine (NVP) is suggested to be greater in pregnant women. We conducted a systematic review and meta-analysis of severe adverse events...
Impact of parental HIV/AIDS on children’s psychological well-being: A systematic review of global literature
This review examines the global literature regarding the impact of parental HIV/AIDS on children’s psychological well-being. Fifty one articles reporting quantitative data from a total of 30 studies were retrieved...
Behavioral interventions to reduce the transmission of HIV infection among sex workers and their clients in low- and middle-income countries
BACKGROUND: Various interventions have been adopted to reduce HIV transmission among sex workers and their clients but the effectiveness of these strategies has yet to be investigated using meta-analytic techniques....
The efficacy of methadone maintenance interventions in reducing illicit opiate use, HIV risk behavior and criminality: a meta-analysis
XST: This is a critical abstract of a systematic review that meets the criteria for inclusion on DARE. Each critical abstract contains a brief summary of the review methods, results...
Treatment of helminth co-infection in individuals with HIV-1: A systematic review of the literature
BACKGROUND AND OBJECTIVES: The HIV-1 pandemic has disproportionately affected individuals in resource-constrained settings. It is important to determine if other prevalent infections affect the progression of HIV-1 in co-infected individuals...
Efficacy of antiretroviral therapy adherence interventions: A research synthesis of trials, 1996 to 2004
OBJECTIVE: To conduct a quantitative review of published trials of antiretroviral therapy (ART) adherence interventions. DESIGN: A research synthesis of published ART adherence intervention outcome studies. SAMPLE: ART adherence intervention...
