Category Archives: Prevention, Engagement and Care Cascade
Structured treatment interruptions (STI) in chronic suppressed HIV infection in adults
BACKGROUND: Although antiretroviral treatment (ART) has led to a decline in morbidity and mortality of HIV-infected patients in developed countries, it has also presented challenges. These challenges include increases in...
Complementary and alternative therapy (CAT) use and highly active antiretroviral therapy (HAART): Current evidence in the literature, 2000–2009
Aim and objective. To determine current evidence about the use of complementary and alternative medicine in the context of highly active antiretroviral therapy. The following objectives included identifying the risks...
Secrets and safety in the age of AIDS: Does HIV disclosure lead to safer sex?
To fuel the HIV/AIDS epidemic, HIV-seropositive individuals must interact unsafely with HIV-seronegative individuals. Research indicates that up to one third of individuals diagnosed with HIV continue to have unprotected sex,...
Systematic review of clinical trials evaluating low doses of stavudine as part of antiretroviral treatment
Stavudine is a nucleoside analogue used for the treatment of HIV-1 infection, as part of highly active antiretroviral treatment. In developing countries, stavudine is used widely, owing to low cost...
Nevirapine once daily: Pharmacology, metabolic profile and efficacy data of the new extended-release formulation
Introduction: Nevirapine (NVP), a non-nucleoside reverse transcriptase inhibitor, has been an important component of HIV infection treatment for many years. Currently, twice-a-day dosing is required for the successful application of...
Bone mineral density in HIV-infected women taking antiretroviral therapy: A systematic review
There is a high prevalence of osteoporosis in HIV-infected patients. Initially described in HIV-positive men, studies have also demonstrated a high prevalence of osteoporosis in HIV-infected women. It would appear...
Behavioral interventions for African Americans to reduce sexual risk of HIV: A meta-analysis of randomized controlled trials
CONTEXT: African Americans constitute 13% of the US population yet account for nearly 50% of new HIV infections. Implementation of efficacious behavioral interventions can help reduce infections in this vulnerable...
Effect of directly observed therapy for highly active antiretroviral therapy on virologic, immunologic, and adherence outcomes: A meta-analysis and systematic review
Introduction: Directly observed therapy of highly active antiretroviral therapy (DOT-HAART) is a feasible adherence intervention. Prospective DOT-HAART studies have shown mixed results, and optimal target groups have yet to be...
Prevalence of bisexual behaviour among bridge population of men who have sex with men in China: A meta-analysis of observational studies
Objective: To integrate the empirical estimates of bisexual behaviour among the bridge population of men who have sex with men (MSM) in China and their HIV and syphilis prevalences stratified...
Virological follow-up of adult patients in antiretroviral treatment programmes in sub-Saharan Africa: A systematic review
Following large-scale roll-out of antiretroviral therapy in sub-Saharan Africa, the non-clinical efficacy of antiretroviral therapy has received little attention. We aimed to systematically review virological efficacy and drug-resistance outcomes of...
Behavioral interventions for improving contraceptive use among women living with HIV
Background: Contraception services can help meet the family planning goals of women living with HIV as well as prevent mother-to-child transmission. Due to the increased availability of antiretroviral therapy, survival...
