Category Archives: Prevention, Engagement and Care Cascade
Social and structural factors associated with HIV disease progression among illicit drug users: A systematic review
OBJECTIVE: To systematically review factors associated with HIV disease progression among illicit drug users, focusing on exposures exogenous to individuals that likely shape access and adherence to HIV treatment. DESIGN:...
Nucleoside reverse transcriptase inhibitors in combination therapy for HIV patients: Systematic review and meta-analysis
Treatment guidelines recommend dual nucleoside reverse transcriptase inhibitors (NRTI ) as a part of combination antiretroviral therapy. The objective of this study was to assess the relative efficacy and toxicity...
Interventions to prevent HIV and Hepatitis C in people who inject drugs: A review of reviews to assess evidence of effectiveness
BACKGROUND: Injecting drug use is a major risk factor for the acquisition and transmission of HIV and Hepatitis C virus (HCV). Prevention of these infections among people who inject drugs...
Cannabinoids for treatment of chronic non-cancer pain: A systematic review of randomized trials
Effective therapeutic options for patients living with chronic pain are limited. The pain relieving effect of cannabinoids remains unclear. A systematic review of randomized controlled trials (RCTs) examining cannabinoids in...
Workplace programmes for HIV and tuberculosis: A systematic review to support development of international guidelines for the health workforce
The health service sector has a vital role to play in delivering human immunodeficiency virus (HIV) and tuberculosis (TB) prevention, treatment and care, yet evidence indicates that healthcare workers (HCWs)...
Levels of adherence required for virologic suppression among newer antiretroviral medications
OBJECTIVE: To determine the adherence levels needed for HIV virologic suppression with newer antiretroviral (ARV) medications, including darunavir, etravirine, and raltegravir. DATA SOURCES: Literature searches of PubMed, MEDLINE (1950-October 2010),...
The paradigm of universal access to HIV-treatment and human rights violation: How do we treat HIV-positive people who use drugs?
HIV-positive people who use drugs (PWUDs) are particularly vulnerable for suboptimal access to highly active antiretroviral therapy (HAART). We conducted a systematic review to identify factors associated with suboptimal HAART...
Can computer-mediated interventions change theoretical mediators of safer sex? A meta-analysis
The purpose of this study was to conduct a meta-analysis of computer-mediated interventions (CMIs) aimed at changing theoretical mediators of safer sex. Meta-analytic aggregation of effect sizes from k =...
Access to and utilisation of health services for the poor in Uganda: A systematic review of available evidence
Inequalities in the burden of disease and access to health care is a prominent concern in Uganda and other sub-Saharan African countries. This is a systematic review of socio-economic differences...
Patient retention in antiretroviral therapy programs up to three years on treatment in sub-Saharan Africa, 2007-2009: Systematic review
Objectives To estimate the proportion of all-cause adult patient attrition from antiretroviral therapy (ART) programs in service delivery settings in sub-Saharan Africa through 36 months on treatment. Methods We identified...
