Category Archives: Prevention, Engagement and Care Cascade
Treatment of acute cryptococcal meningitis in HIV infected adults, with an emphasis on resource-limited settings
BACKGROUND: Despite the advent and increasingly wide availability of antiretroviral therapy, cryptococcal meningitis (CM) remains a significant cause of mortality and morbidity amongst individuals with HIV infection in resource-limited settings....
A systematic review of antiretroviral adherence interventions for HIV-infected people who use drugs
HIV-infected persons who use drugs (PWUDs) are particularly vulnerable for suboptimal combination antiretroviral therapy (cART) adherence. A systematic review of interventions to improve cART adherence and virologic outcomes among HIV-infected...
The cost of treatment and care for people living with HIV infection: Implications of published studies, 1999-2008
Purpose of review: Increasing number of people living with HIV (PLHIV) will require expanded access to health services. Countries need robust and contemporary strategic information on the cost of care...
Optimal monitoring strategies for guiding when to switch first-line antiretroviral therapy regimens for treatment failure in adults and adolescents living with HIV in low-resource settings
BACKGROUND: One of the critical clinical decisions made in antiretroviral therapy (ART) is when to switch from an initial regimen to another due to treatment failure. This complex process requires...
Women, sex, and HIV: social and contextual factors, meta-analysis of published interventions, and implications for practice and research
This article is focused on examining social and contextual factors related to HIV-risk behavior for women. Specifically, this article has three main purposes: to review the literature on selected social...
Evidence base for children affected by HIV and AIDS in low prevalence and concentrated epidemic countries: Applicability to programming guidance from high prevalence countries
As global commitment grows to protect and support children affected by HIV and AIDS, questions remain about how best to meet the needs of these children in low prevalence settings...
Effect of preventive treatment for tuberculosis in adults infected with HIV: Systematic review of randomised placebo controlled trials
OBJECTIVE: To determine whether preventive treatment for tuberculosis in adults infected with HIV reduces the frequency of tuberculosis and overall mortality. DESIGN: Systematic review and data synthesis of randomised placebo...
Complementary and alternative medicine use among HIV-positive people: Research synthesis and implications for HIV care
Use of complementary and alternative medicine (CAM) is prevalent among HIV-positive individuals despite the success of antiretroviral treatments and limited evidence of CAM’s safety and efficacy. To characterize the potential...
Impact of baseline HIV-1 RNA levels on initial highly active antiretroviral therapy outcome: A meta-analysis of 12,370 patients in 21 clinical trials
BACKGROUND: Individual randomized trials of first-line antiretroviral treatment do not consistently show an association between higher baseline HIV-1 RNA and lower efficacy. METHODS: A MEDLINE search identified 21 HIV clinical...
