Category Archives: Prevention, Engagement and Care Cascade
Effectiveness of pediatric antiretroviral therapy in resource-limited settings: A systematic review and meta-analysis
BACKGROUND: Responses to antiretroviral therapy (ART) among human immunodeficiency virus (HIV)-infected children in resource-limited settings have recently been reported, but outcomes vary. We sought to derive pooled estimates of the...
Heterosexual risk of HIV-1 infection per sexual act: Systematic review and meta-analysis of observational studies
We did a systematic review and meta-analysis of observational studies of the risk of HIV-1 transmission per heterosexual contact. 43 publications comprising 25 different study populations were identified. Pooled female-to-male...
Prevalence of bisexual behaviour among bridge population of men who have sex with men in China: A meta-analysis of observational studies
Objective: To integrate the empirical estimates of bisexual behaviour among the bridge population of men who have sex with men (MSM) in China and their HIV and syphilis prevalences stratified...
Patient retention in antiretroviral therapy programs in sub-Saharan Africa: A systematic review
BACKGROUND: Long-term retention of patients in Africa’s rapidly expanding antiretroviral therapy (ART) programs for HIV/AIDS is essential for these programs’ success but has received relatively little attention. In this paper...
Contraception for the HIV-positive woman: A review of interactions between hormonal contraception and antiretroviral therapy
Background. Preventing unintended pregnancy in HIV-positive women can significantly reduce maternal-to-child HIV transmission as well as improve the woman’s overall health. Hormonal contraceptives are safe and effective means to avoid...
Bone mineral density in HIV-infected women taking antiretroviral therapy: A systematic review
There is a high prevalence of osteoporosis in HIV-infected patients. Initially described in HIV-positive men, studies have also demonstrated a high prevalence of osteoporosis in HIV-infected women. It would appear...
The effectiveness of behavioural and psychosocial HIV/STI prevention interventions for MSM in Europe: A systematic review
Given the need of programme planners and policy makers for descriptions of specific interventions and quantitative estimates of intervention effects to make informed decisions concerning prevention funding and research, there...
Role of genetic diversity amongst HIV-1 non-B subtypes in drug resistance: A systematic review of virologic and biochemical evidence
The genetic diversity of HIV-1 has required its classification into types and subtypes. There is controversy as to how and to what extent genetic diversity may affect the emergence of...
Efficacy of new antiretroviral drugs in treatment-experienced HIV-infected patients: A systematic review and meta-analysis of recent randomized controlled trials
OBJECTIVES: We performed a systematic review and meta-analysis of randomized controlled trials (RCTs) to assess the overall efficacy of new antiretroviral drugs, as well as the factors associated with increased...
Utilizing buprenorphine-naloxone to treat illicit and prescription-opioid dependence
OBJECTIVES: To review current evidence on buprenorphine-naloxone (bup/nx) for the treatment of opioid-use disorders, with a focus on strategies for clinical management and office-based patient care. QUALITY OF EVIDENCE: Medline...
