Category Archives: Prevention, Engagement and Care Cascade

Synthesizing gender based HIV interventions in Sub-Sahara Africa: A systematic review of the evidence

2013

Gender is a critical component of HIV and sexual risk interventions. Examining the range, effectiveness and methodological rigor of studies that include a gender based component can inform current interventions...

Acceptability of HIV self-testing: A systematic literature review

2013

BACKGROUND: The uptake of HIV testing and counselling services remains low in risk groups around the world. Fear of stigmatisation, discrimination and breach of confidentiality results in low service usage...

Efficacy and safety of micafungin for invasive candida infections: A meta-analysis of randomized controlled trials

2012

Background Invasive fungal infections such as candidiasis and mold infections cause significant morbidity and mortality in seriously ill patients. Micafungin is an echinocandin antifungal agent with potent activity against most...

Adherence challenges with drugs for pre-exposure prophylaxis to prevent HIV infection

2014

Background There are 34 million people living with human immunodeficiency virus (HIV) worldwide and each year this number increases. Until a vaccine is discovered, the prevention of new HIV infections...

Protease inhibitor-associated QT interval prolongation

2011

OBJECTIVE: To evaluate the literature on protease inhibitor (PI)-associated QT interval prolongation and risk for torsade de pointes in patients infected by HIV. DATA SOURCES: Primary literature was identified through...

Impact of HIV-related stigma on treatment adherence: Systematic review and meta-synthesis

2013

Introduction: Adherence to HIV antiretroviral therapy (ART) is a critical determinant of HIV-1 RNA viral suppression and health outcomes. It is generally accepted that HIV-related stigma is correlated with factors...

Peer-led interventions to reduce HIV risk of youth: A review

2010

One approach in HIV prevention programming targeting youth is to use peer leaders in what is referred to as peer education programming. This paper critically reviews and synthesizes the results...

Systematic review of interventions to prevent the spread of sexually transmitted infections, including HIV, among young people in Europe

2010

AIM: To examine the effectiveness of interventions seeking to prevent the spread of sexually transmitted infections (STIs), including HIV, among young people in the European Union. METHODS: For this systematic...

A review of research on residential programs for people with severe mental illness and co-occurring substance use disorders

2004

Substance use disorder is the most common and clinically significant co-morbidity among clients with severe mental illnesses, associated with poor treatment response, homelessness and other adverse outcomes. Residential programs for...

Syphilis in drug users in low and middle income countries

2010

BACKGROUND: Genital ulcer disease (GUD), including syphilis, is an important cause of morbidity in low and middle income (LMI) countries and syphilis transmission is associated with HIV transmission. METHODS: We...

Reporting of adverse events in randomized controlled trials of highly active antiretroviral therapy: Systematic review

2009

OBJECTIVES: Our objectives were to systematically assess the quality of reporting of adverse events (AEs) in publications of randomized trials of highly active antiretroviral therapy (HAART), and to examine whether...

Economic and quality of life outcomes of antiretroviral therapy for HIV/AIDS in developing countries: A systematic literature review

2009

The impacts of antiretroviral therapy (ART) on quality of life, mental health, labor productivity, and economic wellbeing for people living with HIV/AIDS in developing countries are only beginning to be...

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