Category Archives: Prevention, Engagement and Care Cascade
Interventions to reduce sexual risk for the human immunodeficiency virus in adolescents, 1985-2000: A research synthesis
OBJECTIVE: To summarize studies that have tested the efficacy of human immunodeficiency virus (HIV) sexual risk-reduction interventions in adolescents. DATA SOURCES: Reports were gathered from computerized databases, by contacting individual...
Effectiveness of female controlled barrier methods in preventing sexually transmitted infections and HIV: Current evidence and future research directions
OBJECTIVES: To evaluate evidence for the effectiveness of female controlled physical and chemical barrier methods in preventing STI/HIV transmission, to examine recent reviews on microbicide development, and to highlight promising...
Recreational use of sildenafil by HIV-positive and -negative homosexual/bisexual males
OBJECTIVE: To conduct an epidemiologic review of sildenafil in homosexual and bisexual males focusing on concurrent use with club drugs and/or antiretroviral medications. DATA SOURCES: A search of MEDLINE was...
Tipranavir: The first nonpeptidic protease inhibitor for the treatment of protease resistance
Background: Despite the availability of a growing number of potent antiretroviral agents, efforts to completely suppress viral replication in patients with HIV-1 infection are limited because of the increasing risk...
Systematic review of the effectiveness of mass communication programs to change HIV/AIDS-related behaviors in developing countries
This review systematically examined the effectiveness of 24 mass media interventions on changing human immunodeficiency virus (HIV)-related knowledge, attitudes and behaviors. The intervention studies were published from 1990 through 2004,...
Comparisons of disparities and risks of HIV infection in black and other men who have sex with men in Canada, UK, and USA: A meta-analysis
BACKGROUND: We did a meta-analysis to assess factors associated with disparities in HIV infection in black men who have sex with men (MSM) in Canada, the UK, and the USA....
HIV type-1 drug resistance in treatment-naive patients monitored using minority species assays: A systematic review and meta-analysis
BACKGROUND: The detection of mutations associated with drug resistance in HIV type-1 might be increased by applying minority species assays capable of identifying low frequency mutations in comparison with the...
Treatment, care and support for people co-infected with HIV and hepatitis C: A scoping review
Background: Providing care for people who are co-infected with both HIV and hepatitis C virus (HCV) is becoming increasingly complex and requires integrated prevention, screening, support and programming efforts. We...
Improving the prevention, diagnosis and treatment of TB among people living with HIV: The role of operational research
Operational research is necessary to improve the access to and delivery of tuberculosis prevention, diagnosis and treatment interventions for people living with HIV. We conducted an extensive review of the...
Patient retention in antiretroviral therapy programs in sub-Saharan Africa: A systematic review
BACKGROUND: Long-term retention of patients in Africa’s rapidly expanding antiretroviral therapy (ART) programs for HIV/AIDS is essential for these programs’ success but has received relatively little attention. In this paper...
Prevalence, severity, and duration of thrombocytopenia among HIV patients in the era of highly active antiretroviral therapy
Thrombocytopenia is a clinically relevant outcome in HIV. However, the epidemiology of this condition, including frequency, severity, and duration, has not been well-characterized in the era of highly active antiretroviral...
Interventions to promote linkage to and utilization of HIV medical care among HIV-diagnosed persons: A qualitative systematic review, 1996-2011.
This qualitative systematic review examined interventions that promote linkage to or utilization of HIV care among HIV-diagnosed persons in the United States. We conducted automated searches of electronic databases (i.e.,...
