Category Archives: Prevention, Engagement and Care Cascade
Safety of nevirapine in HIV-infected pregnant women initiating antiretroviral therapy at higher CD4 counts: A systematic review and meta-analysis
BACKGROUND: The package insert for nevirapine (NVP) cautions use in HIV-infected women (including pregnant women) with CD4 counts ≥250 cells/µl. However, recent studies showed that the CD4 count of pregnant...
More than 20 years of research into the quality of life of people with HIV and AIDS–a descriptive review of study characteristics and methodological approaches of published empirical studies
BACKGROUND: The quality of life of people living with HIV and AIDS (PLWHA) is becoming increasingly important–a fact that is also reflected in extensive research efforts. Owing to the almost...
Nevirapine-based regimens in HIV-infected antiretroviral-naive patients: Systematic review and meta-analysis of randomized controlled trials.
BACKGROUND: Nevirapine belongs to the group of non-nucleoside reverse transcriptase inhibitors (NNRTIs) and is commonly administered in first-line treatment of HIV infection. OBJECTIVE: Systematic review and meta-analysis was undertaken to...
Depression treatment enhances adherence to antiretroviral therapy: A meta-analysis
BACKGROUND: Depression is a risk factor for nonadherence to HIV/AIDS treatment. PURPOSE: A meta-analysis was conducted to examine whether treatment of depression and psychological distress improves antiretroviral therapy adherence. METHODS:...
Factors that affect HIV testing and counseling services among heterosexuals in Canada and the United Kingdom: An integrated review
OBJECTIVE: To examine factors that affect the utilization of HIV testing and counseling (HTC) services among heterosexual populations in Canada and the U.K. METHODS: We conducted an integrated review of...
Immunological and virological benefits resulted from short-course treatment during primary HIV infection: A meta-analysis
OBJECTIVES: To assess the potential immunological and virological effects that result from short-course antiretroviral treatment during primary HIV infection (PHI). And to investigate whether treatment initiation time, treatment duration and...
Are HIV epidemics among men who have sex with men emerging in the Middle East and North Africa?: A systematic review and data synthesis
BACKGROUND: Men who have sex with men (MSM) bear a disproportionately higher burden of HIV infection than the general population. MSM in the Middle East and North Africa (MENA) are...
Management of HIV-associated tuberculosis in resource-limited settings: A state-of-the-art review
The HIV-associated tuberculosis (TB) epidemic remains a huge challenge to public health in resource-limited settings. Reducing the nearly 0.5 million deaths that result each year has been identified as a...
Effects of physician-nurse substitution on clinical parameters: A systematic review and meta-analysis
BACKGROUND: Physicians’ shortage in many countries and demands of high-quality and affordable care make physician-nurse substitution an appealing workforce strategy. The objective of this study is to conduct a systematic...
Experiences integrating delivery of maternal and child health services with childhood immunization programs: Systematic review update
BACKGROUND: The World Health Organization and the United Nations Children’s Fund promote integration of maternal and child health (MCH) and immunization services as a strategy to strengthen immunization programs. We...
