Category Archives: Prevention, Engagement and Care Cascade
HIV sexual risk-reduction interventions for youth: A review and methodological critique of randomized controlled trials
The authors review and provide a methodological critique of randomized controlled studies of HIV risk reduction interventions that measured sexual risk behavior outcomes with adolescents. Studies conducted in school, community,...
Timing of antiretroviral therapy for HIV in the setting of TB treatment
The convergent human immunodeficiency virus (HIV) and tuberculosis (TB) pandemics continue to collectively exact significant morbidity and mortality worldwide. Highly active antiretroviral therapy (HAART) has been a critical component in...
The impact of HIV treatment on risk behaviour in developing countries: A systematic review
In developing countries, access to antiretroviral therapy (ART) is improving as HIV treatment becomes a greater priority in the global fight against AIDS. While ART has clearly beneficial clinical effects,...
Very late initiation of HAART impairs treatment response at 48 and 96 weeks: Results from a meta-analysis of randomized clinical trials
BACKGROUND: Initiation of highly active antiretroviral therapy (HAART) with low CD4 lymphocyte counts is associated with AIDS-related and non-AIDS-related events and increased mortality. However, no clear association has been found...
Systematic review of the efficacy of antiretroviral therapies for reducing the risk of mother-to-child transmission of HIV infection
OBJECTIVE: To evaluate the efficacy of antiretroviral therapies in reducing the risk of mother-to-child transmission of HIV infection. METHODS: Systematic review and meta-analysis of randomized controlled trials. Clinical trials of...
Iron supplementation for reducing morbidity and mortality in children with HIV
BACKGROUND: The most prevalent haematologic disturbance associated with HIV in children (apart from CD4 lymphocytopenia) is anaemia. Anaemia associated with HIV arises from multiple mechanisms, including the direct inhibitory effect...
Home-based care for reducing morbidity and mortality in people infected with HIV/AIDS
BACKGROUND: Home-based care (HBC), to promote quality-of-life and limit hospital care, is used in many countries, especially where public health services are overburdened. OBJECTIVES: This review assessed the effects of...
Estimating HIV prevalence and risk behaviors of transgender persons in the United States: A systematic review
Transgender populations in the United States have been impacted by the HIV/AIDS epidemic. This systematic review estimates the prevalence of HIV infection and risk behaviors of transgender persons. Comprehensive searches...
The impact of African Americans’ beliefs about HIV medical care on treatment adherence: A systematic review and recommendations for interventions.
Disparities in access to and retention of regular HIV medical treatment persist among African Americans living with HIV. Many scholars believe that the mistrust of health care held by many...
