Category Archives: Prevention, Engagement and Care Cascade
Baseline CD4+ cell count, not viral load, correlates with virologic suppression induced by potent antiretroviral therapy
2001
OBJECTIVE: To investigate the relationship between viral load suppression and baseline viral load as well as that between viral load suppression and baseline CD4(+) cell count. DESIGN: Meta-analysis of published...
HIV in the Middle East and North Africa: Priority, culture, and control
2013
OBJECTIVES: This study aimed to assess the priority of HIV/AIDS in the Middle East and North Africa region and compare it with other regions. This review examines the social, cultural...
Therapeutic drug monitoring and drug-drug interactions involving antiretroviral drugs
2005
The consensus of current international guidelines for the treatment of HIV infection is that data on therapeutic drug monitoring (TDM) of non-nucleoside reverse transcriptase inhibitors (NNRTIs) and protease inhibitors (Pls)...
Once-daily abacavir in place of twice-daily administration
2005
OBJECTIVE: To review the safety and efficacy of a once-daily dosage regimen for abacavir, a nucleoside reverse transcriptase inhibitor. DATA SOURCES: English-language MEDLINE and Iowa Drug Information Service database reports...
Epidemiology of HIV-related neuropathy: A systematic literature review
2012
We sought to identify and summarize the incidence and prevalence of neuropathy among HIV patients and subgroups. A systematic search of the literature was performed using MEDLINE and EMBASE. The...
Relative risk for HIV infection among men who have sex with men engaging in different roles in anal sex: A systematic review and meta-analysis on global data
2014
We systematically reviewed and meta-analyzed global data on the relative risk for HIV infection among men who have sex with men (MSM) engaging in different roles in anal sex. MSM...
Focusing “down low”: Bisexual black men, HIV risk and heterosexual transmission
2005
INTRODUCTION: Black men who have sex with men (MSM) and women but who do not identify as gay or disclose their bisexual activities to main female partners, also known as...
Informal caregivers of persons with HIV/AIDS: A review and analysis
2003
Due to advanced antiretroviral treatments, persons with HIV/AIDS (PWH/As) live longer and experience various physical and cognitive impairments during the course of their disease. Often, informal caregivers assist PWH/As to...
Non-injection drug use and HIV disease progression in the era of combination antiretroviral therapy
2011
Little is known about the effects of non-injection drug use (NIDU) on HIV antiretroviral treatment outcomes. We conducted a systematic literature search and identified nine publications from prospective cohort studies...
Vaginal disinfection for preventing mother-to-child transmission of HIV infection
2005
BACKGROUND: Mother-to-child transmission (MTCT) of HIV infection is one of the most tragic consequences of the HIV epidemic, especially in resource-limited countries, resulting in about 650 000 new paediatric HIV...
Older persons’ exclusion from sexually transmitted disease risk-reduction clinical trials
2007
BACKGROUND: The incidence of HIV and AIDS is growing faster among individuals 50 and older compared to those under 40. Although the majority of clinical trials aimed at treating diseases...
Barriers to participation in HIV drug trials: A systematic review
2006
The enrolling of adequate participants into HIV experimental drug trials presents an important challenge. We systematically reviewed the literature to identify barriers and concerns amongst HIV patients to participation in...
