Category Archives: Prevention, Engagement and Care Cascade
Maternal HIV infection and antiretroviral therapy in pregnancy: Implications for vertical transmission, fetal safety, and long-term infant outcomes
HIV mother-to-child transmission (MTCT) continues to pose a significant public health challenge, especially in regions with limited resources, although the worldwide distribution of antiretroviral therapy (ART) has drastically lowered the...
Integration of mental health and HIV service delivery in low- and middle-income countries: A systematic review of effectiveness
Human immunodeficiency virus (HIV) and mental health have complex, bidirectional impacts. Integrated service delivery, especially in low- and middle-income countries (LMICs) where resources are most limited and the burden of...
Oral pre-exposure prophylaxis retention among men who have sex with men and transgender persons: Systematic review and meta-analysis
Successful implementation of oral pre-exposure prophylaxis (PrEP) requires retention in PrEP care among those with an increased likelihood of HIV. This study aimed to estimate the proportion of retention on...
A scoping review of grey zone use for transfusion-transmitted infection screening among blood donors
BACKGROUND AND OBJECTIVES: Screening for transfusion-transmitted infections (TTIs) among blood donors is done using qualitative screening assays. Screening values that are close to cut-off values lie in the uncertainty zone,...
Prevalence and associated factors of undernutrition among adults living with HIV in Ethiopia: A systematic review and meta-analysis
BACKGROUND: The study aimed to assess the pooled prevalence of undernutrition and its associated factors among HIV-positive adults in Ethiopia. METHODS: Intensive searches were conducted using PubMed, EMBASE (Elsevier), Cochrane,...
High HIV viral suppression among adults receiving WHO-recommended first-line dolutegravir-based antiretroviral therapy in low- and middle-income countries: A systematic review and meta-analysis of programmatic evidence
Background This systematic review and meta-analysis assessed viral suppression among adults receiving WHO-recommended first-line dolutegravir-based ART in programmatic settings in low- and middle-income countries (LMICs). Methods A systematic search of...
Interventions to support breastfeeding among mothers living with HIV: A systematic review and meta-analysis of randomized controlled trials
BACKGROUND: Breastfeeding improves infant survival, especially in low-resource settings. Although the risk of postnatal transmission is below 1% among virologically suppressed mothers living with HIV, exclusive breastfeeding (EBF) rates and...
The magnitude and patterns of acquired drug resistanace mutations and circulating HIV-1 subtypes in HIV patients in Tanzania, a systematic review and meta-analysis
The emergence and spread of HIV drug resistance mutations (DRMs) pose a threat to current and future treatment options. To inform policy, this review aimed to determine the magnitude and...
Prevalence of low-level viremia and related influencing factors among people living with HIV in China: A systematic review and meta-analysis
Introduction The promotion and application of ART have significantly reduced the mortality rate of AIDS patients in China, but the problem of LLV that follows cannot be ignored. LLV is...
Effects of Moringa oleifera supplementation on immune and nutritional biomarkers in adults living with HIV: A systematic review and meta-analysis
BACKGROUND: Moringa oleifera (MO) is widely used as an adjunctive therapy for individuals living with HIV (PLWH) due to its nutritional and immune-modulating properties. OBJECTIVE: To systematically evaluate the effects...
