Category Archives: Prevention, Engagement and Care Cascade
Perspective of people living with HIV and healthcare workers on the uptake, barriers, and benefits of multimonth dispensing: A qualitative systematic review
INTRODUCTION: Multimonth dispensing (MMD) is a strategy in the HIV care continuum for people living with HIV (PLWH), especially for those who are virally suppressed. With the increase in MMD...
Simulation modeling for the design and evaluation of HIV drug resistance interventions: A systematic review of literature
Background The utility of antiretroviral therapy (ART) in the management of human immunodeficiency virus (HIV) is being challenged by growing HIV drug resistance (HIVDR). Although simulation modelling is useful for...
Integration of HIV, Hepatitis B, and C, and sexually transmitted infections services: A scoping review of the benefits and challenges
BACKGROUND: Integrating clinical programs and services is a cost-effective approach that can improve health and system outcomes. This review aimed to provide an overview of the benefits and challenges of...
Interventions to improve access to sexual and reproductive health services for adolescents living with HIV in sub-Saharan Africa: A scoping review
OBJECTIVE: Adolescents living with HIV (ALHIV) face barriers to accessing sexual and reproductive health (SRH) services, negatively affecting their health and quality of life. These challenges are particularly pronounced in...
Prevalence and risk factors for cytomegalovirus retinitis among people living with HIV in sub-Saharan Africa in the antiretroviral therapy era: A systematic review and meta-analysis
Cytomegalovirus retinitis has remained an alarming and potentially vision-threatening opportunistic disease in the population living with HIV, especially in cases of extreme immunosuppression. Although the introduction of antiretroviral therapy has...
Exploring the potential of cognitive intra-individual variability in HIV care and research in adults with HIV: A concept analysis
Cognitive intraindividual variability (IIV) refers to the variability in one’s ability to sustain consistent cognitive performance. This phenomenon is linked to the emergence of cognitive impairment and dementia. The aim...
Effectiveness of digital health interventions for improving antiretroviral therapy outcomes in people with HIV: Meta-analysis and trial sequential analysis of randomized controlled trials
Background: Digital health interventions (DHIs) are increasingly used to support antiretroviral therapy (ART) management among people living with HIV. However, existing systematic reviews have largely focused on single intervention types or...
Impact of dolutegravir-based regimens on patient satisfaction and quality of life among people living with HIV: A systematic review and meta-analysis
Background Despite the global scale up of dolutegravir (DTG)-based regimens as the preferred first-line therapy for persons living with HIV (PLHIV), no comprehensive evidence exists on its effect on patient-reported...
The burden of HIV-related stigma on clinical and quality of life outcomes: results from a systematic literature review
BACKGROUND: HIV-related stigma adversely impacts people with HIV. As part of a systematic literature review (SLR) to evaluate 6 research questions on HIV-related stigma among people with HIV, data from...
Structural competency as a global framework for syndemic HIV care: A critical synthesis
The co-occurrence of HIV with mental health disorders, substance use, and tuberculosis continues to constitute significant global public health issues. Syndemic theory elucidates how these conditions interact synergistically to exacerbate...
Temporal shifts in antiretroviral therapy regimens and metabolic outcomes in people living with HIV: A systematic review and meta-analysis
Introduction Antiretroviral therapy (ART) for people living with HIV has led to dramatically reduced mortality and improved life expectancy. This achievement is accompanied by a higher risk for metabolic and...
Condom use and associated factors among people living with HIV/AIDS on anti-retroviral therapy (ART) in Ethiopia: A systematic review and meta-analysis
Condom use remains a crucial preventive measure for individuals undergoing antiretroviral therapy (ART) in the fight against HIV/AIDS. This review and meta-analysis aimed to determine the pooled prevalence of condom...
