Category Archives: Prevention, Engagement and Care Cascade
Management of low-level HIV viremia during antiretroviral therapy: Delphi consensus statement and appraisal of the evidence
Objective While antiretroviral therapy (ART) is highly effective, detection of low levels of HIV-1 RNA in plasma is common in treated individuals. Given the uncertainties on the topic, we convened...
State of HIV costing in Latin America and the Caribbean: A systematic literature review
OBJECTIVES: To summarize available data on unit costs for human immunodeficiency virus (HIV) testing, prevention, and care interventions in Latin America and the Caribbean. METHODS: We conducted a systematic literature...
Reproductive health needs of HIV serodiscordant couples: A systematic review
Objectives HIV is closely linked to reproductive and sexual health. HIV Serodiscordant couples face significant social, reproductive, and sexual challenges. This systematic review aimed to identify their reproductive health needs....
An integrative review of the literature examining sexual relationship power, depressive symptoms, silencing the self, and HIV vulnerability for women in the United States
The purpose of our integrative review was to synthesize the literature examining relationships between depressive symptoms, silencing the self (STS), sexual relationship power (SRP), and HIV vulnerability among women in...
Health outcomes associated with loneliness and social isolation in older adults living with HIV: A systematic review
Self-management of HIV is crucial to reduce disease-related negative health outcomes. Loneliness and social isolation are associated with poor disease self-management (e.g., medication non-adherence and care disengagement) in younger people...
Identifying effective strategies for improving engagement in HIV prevention and care among transgender persons in the United States: A systematic review
This systematic review synthesized published literature (2000–2023) to identify HIV interventions specifically designed for transgender persons in the United States (PROSPERO registration number: CRD42021256460). The review also summarized strategies for...
Analysis of drug-drug interactions in patients with HIV and metabolic syndrome
BACKGROUND: People with HIV (PWH) are living longer directly related to benefits of highly effective antiretroviral therapy (ART). However, concurrent with improved longevity is the growing prevalence of metabolic comorbidities...
Delving deeper into the mechanisms fundamental to HIV-associated immunopathology using single-cell sequencing techniques: A scoping review of current literature
Human immunodeficiency virus (HIV) infection has evolved into an established global pandemic over the past four decades; however, despite massive research investment globally, the precise underlying mechanisms which are fundamental...
A systematic review and narrative synthesis of factors affecting pre-exposure prophylaxis willingness among Black women for HIV prevention
Pre-exposure prophylaxis (PrEP) can significantly reduce human immunodeficiency virus (HIV) transmission among Black women in the United States (U.S.), a group disproportionately affected by HIV. However, PrEP uptake in this...
The viral load monitoring cascade in HIV treatment programmes in sub-Saharan Africa: A systematic review
BACKGROUND: The United Nations’ 95-95-95 (95% of people with HIV being aware of their diagnosis, 95% of those aware of their diagnosis being on treatment and 95% achieving viral suppression)...
Exploring intervention frameworks to improve utilization of elimination of mother-to-child transmission services in Africa: A scoping review
BACKGROUND: Over the past two decades, intervention strategies to improve the use of the elimination of mother-to-child transmission (EMTCT) services have been implemented for several reasons. The reasons include elimination...
HIV vaccination: Navigating the path to a transformative breakthrough-A review of current evidence
BACKGROUND AND AIM: Human immunodeficiency virus (HIV) remains a significant global health challenge, with approximately 39 million people living with HIV worldwide as of 2022. Despite progress in antiretroviral therapy,...
