Category Archives: Prevention, Engagement and Care Cascade
Web-based service provision of HIV, viral hepatitis, and sexually transmitted infection prevention, testing, linkage, and treatment for key populations: Systematic review and meta-analysis
BACKGROUND: Despite the growth of web-based interventions for HIV, viral hepatitis (VH), and sexually transmitted infections (STIs) for key populations, the evidence for the effectiveness of these interventions has not...
Mental health problems across the HIV care continuum for adolescents living with HIV in sub-Saharan Africa: A scoping review
Mental health problems (e.g., anxiety, depression) are frequently experienced by adolescents living with HIV (ALWH) and can worsen HIV-related outcomes. This scoping review synthesizes the existing research on ALWHs’ mental...
The mother-to-child transmission of HIV-1 and profile of viral reservoirs in pediatric population: A systematic review with meta-analysis of the Cameroonian studies
Background: The mother-to-child transmission of HIV-1 (MTCT) remains on the major route of HIV-transmission among pediatric populations in Africa. Though a prevention of MTCT (PMTCT) high-priority country, data on the MTCT...
A qualitative systematic literature review of the role of U.S. pharmacists in prescribing pre-exposure prophylaxis (PrEP)
Pre-Exposure Prophylaxis (PrEP) is an effective treatment to combat the human immunodeficiency virus (HIV) endemic, but the uptake of PrEP has been low in the United States (U.S.). While individuals...
Virological failure and adherence to antiretroviral therapy in adolescents and young adults living with human immunodeficiency virus
Objective: HIV (human immunodeficiency virus) infection remains a major public health challenge. Infected young people at any age are less likely to adhere to care in a timely manner and to...
The prevalence of HIV-infected patients with virological suppression but a CD4+ T-cell count of ≤ 200 cells/mm3 after highly active antiretroviral therapy initiation: A meta-analysis
Highly active antiretroviral therapy (HAART) strongly inhibits HIV replication. However, many patients show suboptimal immune recovery (SIR), as defined by virological suppression (i.e. low viral load) with a CD4+ T-cell count...
A systematic review and meta-analysis to estimate the time from HIV infection to diagnosis for people with HIV
Timely HIV diagnosis is critical to minimizing transmission events. We sought to estimate the meantime from HIV infection to diagnosis and its temporal trend among people with HIV. Following Preferred...
Barriers and facilitators to HIV pre-exposure prophylaxis uptake, adherence, and persistence among transgender populations in the United States: A systematic review
HIV pre-exposure prophylaxis (PrEP) is highly effective at preventing HIV; however, PrEP use among transgender individuals remains low. We conducted a systematic review to identify barriers and facilitators to PrEP...
Factors associated with post-treatment control of viral load in HIV-infected patients: A systematic review and meta-analysis
BACKGROUND: This study aimed to investigate the factors associated with maintenance of viral suppression after antiretroviral therapy (ART) discontinuation. METHODS: Databases were searched for studies published between 1 January, 2011,...