Category Archives: Prevention, Engagement and Care Cascade
Antenatal depression and its predictors among HIV positive women in Sub-Saharan Africa; a systematic review and meta-analysis
BACKGROUND: Antenatal depression in Human Immunodeficiency Virus (HIV) positive pregnant women can have significant adverse effects on both the mother and newborns, yet it is often overlooked in pregnancy care...
Clinical pharmacology considerations and drug-drug interactions with long-acting cabotegravir and rilpivirine relevant to sub-Saharan Africa
Long-acting injectable (LAI) cabotegravir and rilpivirine for HIV treatment and LAI cabotegravir for pre-exposure HIV prophylaxis are being rolled out in a multitude of countries worldwide. Due to the prolonged...
Repercussions of the COVID-19 pandemic on the HIV care continuum and related factors in economically disadvantaged nations: An integrated analysis using mixed-methods systematic review
BACKGROUND: The COVID-19 pandemic affected the self-management and care of people living with HIV, requiring adaptations in the way health services are provided. However, it is unclear how these changes...
Sexual behavior among emerging adults in Africa: A systematic review and meta-analysis
BACKGROUND: Estimates on sexual behavior (SB) among emerging adults (EmA) is varied in literature, which presents a challenge when designing targeted interventions. We aimed to summarize literature on prevalence and...
Missed opportunities for guidance on sexually transmitted infection services: A global review of national HIV PrEP guidance
OBJECTIVES: People who use or would benefit from pre-exposure prophylaxis (PrEP) for HIV infection are disproportionately affected by sexually transmitted infections (STIs). Integrating STI services when offering PrEP fosters synergies...
A systematic review on advance care planning for people living with HIV: Insights from the studies of persons without HIV
With advances in medicine, HIV has evolved into a chronic condition for people living with HIV (PLWH). However, many PLWH do not engage in advance care planning (ACP), and it...
Low clinical impact of HIV drug resistance mutations in oral pre-exposure prophylaxis: A systematic review and meta-analysis
Introduction Despite the widespread use of pre-exposure prophylaxis (PrEP) in preventing human immunodeficiency virus (HIV) transmission, scant information on HIV drug resistance mutations (DRMs) has been gathered over the past...
Magnitude and risk factors of mother-to-child transmission of HIV among HIV-exposed infants after Option B+ implementation in Ethiopia: A systematic review and meta-analysis
Background Mother-to-child transmission (MTCT) of the human immunodeficiency virus (HIV) remains a major public health challenge in Ethiopia. The objective of this review was to assess the pooled magnitude of...
Assessing structural racism and discrimination along the pre-exposure prophylaxis continuum: A systematic review
Structural racism and discrimination (SRD) is deeply embedded across U.S. healthcare institutions, but its impact on health outcomes is challenging to assess. The purpose of this systematic literature review is...
Telehealth models for PrEP delivery: A systematic review of acceptability, implementation, and impact on the PrEP care continuum in the United States
Pre-exposure prophylaxis (PrEP) is pivotal in curbing HIV transmission and is integral to the national plan to end the HIV epidemic in the United States (US). Nonetheless, widespread PrEP adoption...
Population percentage and population size of men who have sex with men in the United States, 2017–2021: Meta-analysis of 5 population-based surveys
BACKGROUND: Male-to-male sexual transmission continues to account for the greatest proportion of new HIV diagnoses in the United States. However, calculating population-specific surveillance metrics for HIV and other sexually transmitted...
