Category Archives: Prevention, Engagement and Care Cascade

The risk of sexual transmission of HIV in individuals with low-level HIV viraemia: A systematic review

2023

BACKGROUND: The risk of sexual transmission of HIV from individuals with low-level HIV viraemia receiving antiretroviral therapy (ART) has important public health implications, especially in resource-limited settings that use alternatives...

Adverse perinatal outcomes attributable to HIV in sub-Saharan Africa from 1990 to 2020: Systematic review and meta-analyses

2023

Background: Maternal HIV infection and antiretroviral drugs (ARVs) are associated with increased risks of adverse perinatal outcomes. The vast majority of pregnant women living with HIV (WLHIV) reside in sub-Saharan Africa....

Characterizing blood pressure trajectories in people living with HIV following antiretroviral therapy: A systematic review

2023

Objectives: The advent of antiretroviral therapy (ART) has reduced AIDS-related morbidity and mortality among people living with HIV (PLWH). Due to increased survival, PLWH have now been found to be at...

The use of azithromycin and pyrimethamine for treatment of cerebral toxoplasmosis in human immunodeficiency virus-infected patients: A systematic review

2023

PURPOSE: Toxoplasma gondii is a parasite that is widely distributed around the globe and can cause brain inflammation, particularly in immunosuppressed patients such as those diagnosed with human immunodeficiency virus...

Integration of sexually transmitted infection and HIV pre-exposure prophylaxis services in sub-Saharan Africa: A scoping review

2023

BACKGROUND: Persons living in sub-Saharan Africa (SSA) face disproportionate risk from overlapping epidemics of HIV and bacterial sexually transmitted infections (STIs). Pre-exposure prophylaxis (PrEP) for prevention is gradually being scaled...

Using a structural-ecological model to facilitate adoption of preexposure prophylaxis among latinx sexual minority men: A systematic literature review

2023

Research has consistently shown that individual, interpersonal, community and structural factors influence the degree to which individuals’ access and utilize health care services, and these factors may play a role...

Best practices to increase engagement and retention in hepatitis C care among people who use drugs

2023

Key take-home messages

Doxycycline prophylaxis for the prevention of bacterial sexually transmitted infections (STIs)

2023

Key take-home messages

Pre-exposure prophylaxis (PrEP) for HIV prevention among people who inject drugs: A global mapping of service delivery

2023

BACKGROUND: The World Health Organization (WHO) recommends oral pre-exposure prophylaxis (PrEP) for all people at substantial risk of HIV as part of combination prevention. The extent to which this recommendation...

Does engagement in HIV care affect screening, diagnosis, and control of noncommunicable diseases in sub-Saharan Africa? A systematic review and meta-analysis

2023

OBJECTIVE: Low- and middle-income countries are facing a growing burden of noncommunicable diseases (NCDs). Providing HIV treatment may also provide opportunities to increase access to NCD services in under-resourced environments....

Prevalence of Mycoplasma genitalium infection among HIV PrEP users: A systematic review and meta-analysis

2023

Objectives: To summarise the prevalence of Mycoplasma genitalium (MG) and antibiotic-resistant MG infection among HIV pre-exposure prophylaxis (PrEP) users. Methods: We searched MEDLINE, Embase, Web of Science and Global Index Medicus up to 30...

Can contingency management solve the problem of adherence to antiretroviral therapy in drug-dependent individuals?

2023

Drug misuse among people living with HIV (human immunodeficiency virus) is associated with higher mortality. It is a frequently observed reason for treatment abandonment, with people who misuse drugs showing...

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